Beyond Hill-Type Models: Aligning Experiments and Modeling to Understand Dynamic Muscle Function

Muscle models underpin how exercise, rehabilitation, and human-movement sciences infer muscle force during activity, yet profound gaps remain between traditional measures and models of muscle function and the dynamic features of muscle in natural movement. We review evidence for these gaps, highlight new experiments to bridge them, and suggest directions to improve models of dynamic muscle function. Summary: We propose reframing muscle as a dynamic mechanical system, integrating new experiments and models to predict function during natural movement.

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Publication Details

Journal
Exercise and Sport Sciences Reviews
Published
2026-10-09
DOI
https://doi.org/10.1249/jes.0000000000000399
Primary Topic
Muscle activation and electromyography studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Beyond Hill-Type Models: Aligning Experiments and Modeling to Understand Dynamic Muscle Function

Manny Azizi, Daley Monica, Tim van der Zee, Jenna Monroy et al.
Exercise and Sport Sciences Reviews
Muscle activation and electromyography studies
article

Beyond Hill-Type Models: Aligning Experiments and Modeling to Understand Dynamic Muscle Function

Manny Azizi, Daley Monica, Tim van der Zee, Jenna Monroy, Kiisa Nishikawa, Jeffrey Olberding, Simon Sponberg, Carissa Mallonee, Ethan Wold, Caitlin Bemis
article en

Abstract

Muscle models underpin how exercise, rehabilitation, and human-movement sciences infer muscle force during activity, yet profound gaps remain between traditional measures and models of muscle function and the dynamic features of muscle in natural movement. We review evidence for these gaps, highlight new experiments to bridge them, and suggest directions to improve models of dynamic muscle function. Summary: We propose reframing muscle as a dynamic mechanical system, integrating new experiments and models to predict function during natural movement.

Exercise and Sport Sciences Reviews
Georgia Institute of Technology (US), California State University, Fullerton (US), Scripps College (US), Northern Arizona University (US), University of California, Irvine (US), University of Chicago (US), KU Leuven (BE)
Openalex Percentile: Top 24%
Muscle activation and electromyography studies
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Beyond Hill-Type Models: Aligning Experiments and Modeling to Understand Dynamic Muscle Function — Manny Azizi, Daley Monica, et al. · Exercise and Sport Sciences Reviews (2026) | TGRS Research Map | TGRS