Changes in Bladder Outlet Obstruction After Photoselective Vaporization of the Prostate in Men With and Without Detrusor Underactivity: A Retrospective Propensity Score‐Matched Study

ABSTRACT Objectives To compare symptomatic improvement after photoselective vaporization of the prostate (PVP) between patients with and without detrusor underactivity (DU), together with objective changes in urodynamic parameters assessed by pressure‐flow study (PFS). Methods This single‐center retrospective study evaluated 136 benign prostatic hyperplasia (BPH) patients treated with a 180 W PVP‐XPS system from 2020 through 2025. The patients were divided into DU and non‐DU groups based on the bladder contractility index (BCI), with DU defined as BCI < 100. We retrospectively analyzed selected patients with BPH and clinically or urodynamically relevant bladder outlet obstruction (BOO) who underwent PVP and completed PFS before and 6 months after surgery. Propensity score matching (PSM) was applied to adjust for age and the baseline BOO index (BOOI). Results A total of 105 patients were included in the final analysis and 53 were in the DU group. The DU group had a significantly lower BOOI (48.6 ± 17.5 vs. 71.4 ± 32.3, p < 0.01) than the non‐DU group. After PSM, age and baseline BOOI were well balanced, but BCI remained significantly different. No significant differences between the two groups were observed in questionnaire scores or uroflowmetry findings at 6 months after surgery. The BOOI at 6 months after surgery was not significantly different between the DU group (13.4 ± 13.7) and the non‐DU group (13.7 ± 19.3) ( p = 0.93). BOOI reduction was also not significantly different between the DU group (−37.0 ± 24.1) and the non‐DU group (−36.2 ± 24.5) ( p = 0.90). Conclusion In selected patients with clinically or urodynamically relevant BOO, significant improvements in BOOI and LUTS were observed in patients with DU after PVP, with no statistically significant between‐group differences detected at 6 months.

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Journal
LUTS Lower Urinary Tract Symptoms
Published
2026-10-09
DOI
https://doi.org/10.1111/luts.70100
Primary Topic
Urinary Bladder and Prostate Research
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article
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article

Changes in Bladder Outlet Obstruction After Photoselective Vaporization of the Prostate in Men With and Without Detrusor Underactivity: A Retrospective Propensity Score‐Matched Study

Toshiaki Tanaka, Yuki Kyoda, Ko Kobayashi, Kohei Hashimoto et al.
LUTS Lower Urinary Tract Symptoms
Urinary Bladder and Prostate Research
article

Changes in Bladder Outlet Obstruction After Photoselective Vaporization of the Prostate in Men With and Without Detrusor Underactivity: A Retrospective Propensity Score‐Matched Study

Toshiaki Tanaka, Yuki Kyoda, Ko Kobayashi, Kohei Hashimoto, Naoya Masumori, Jurai Shibuya
article en

Abstract

ABSTRACT Objectives To compare symptomatic improvement after photoselective vaporization of the prostate (PVP) between patients with and without detrusor underactivity (DU), together with objective changes in urodynamic parameters assessed by pressure‐flow study (PFS). Methods This single‐center retrospective study evaluated 136 benign prostatic hyperplasia (BPH) patients treated with a 180 W PVP‐XPS system from 2020 through 2025. The patients were divided into DU and non‐DU groups based on the bladder contractility index (BCI), with DU defined as BCI < 100. We retrospectively analyzed selected patients with BPH and clinically or urodynamically relevant bladder outlet obstruction (BOO) who underwent PVP and completed PFS before and 6 months after surgery. Propensity score matching (PSM) was applied to adjust for age and the baseline BOO index (BOOI). Results A total of 105 patients were included in the final analysis and 53 were in the DU group. The DU group had a significantly lower BOOI (48.6 ± 17.5 vs. 71.4 ± 32.3, p < 0.01) than the non‐DU group. After PSM, age and baseline BOOI were well balanced, but BCI remained significantly different. No significant differences between the two groups were observed in questionnaire scores or uroflowmetry findings at 6 months after surgery. The BOOI at 6 months after surgery was not significantly different between the DU group (13.4 ± 13.7) and the non‐DU group (13.7 ± 19.3) ( p = 0.93). BOOI reduction was also not significantly different between the DU group (−37.0 ± 24.1) and the non‐DU group (−36.2 ± 24.5) ( p = 0.90). Conclusion In selected patients with clinically or urodynamically relevant BOO, significant improvements in BOOI and LUTS were observed in patients with DU after PVP, with no statistically significant between‐group differences detected at 6 months.

LUTS Lower Urinary Tract SymptomsVol. 18(6)
Sapporo Medical University (JP)
Openalex Percentile: Top 9%
Urinary Bladder and Prostate Research
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