Inhibition of WNT signaling sensitizes CRC cells to anti-tumor effects of retinoids: basis for new drug combinations in oncology
: Inhibiting WNT signaling effectively sensitizes CRC cells to the anti-tumor effects of retinoids. These findings have important clinical significance for designing new drug combinations against CRC.
Authors
- Caroline O. B. Facey
- Victoria Oluwajuwon Hunsu
- Bruce M. Boman (ORCID: https://orcid.org/0000-0002-1335-9149)
- Lynn M. Opdenaker
Institutions
- Thomas Jefferson University (US)
- University of Delaware (US)
Publication Details
- Journal
- Cancer Biology & Therapy
- Published
- 2026-10-08
- DOI
- https://doi.org/10.1080/15384047.2026.2732738
- Primary Topic
- Wnt/β-catenin signaling in development and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00