The Bioregulatory Model of Organismal Physiological Structure. Part I and Part II

This two-part study presents an integral bioregulatory model of the organism's physiological structure, unifying the foundational principles of ancient medical traditions into a cohesive framework through the lens of modern biocybernetics, topological symmetry, and network physiology. While Part I maps the structural-matrix logic of the organism's peripheral channels, Part II extends this framework to the level of central axial control systems. In Part I, through a geometric and topological reconstruction of the "Great Circuit of Qi Circulation," the authors complete the systemic synthesis initiated by Tibetan medicine. While the historical Tibetan model remained constrained by a ten-organ paradigm, the proposed framework expands the bio-systemic architecture to integrate all twelve classical principal meridians into a universal duodecimal matrix. Furthermore, whereas the Tibetan synthesis encompassed only Chinese and Indian Ayurvedic traditions, the proposed concept additionally maps the principles of Unani medicine within a single matrix structure, establishing its four essential humors (Akhlats) as emergent properties of the system. By applying symmetry principles, the study identifies novel types of analogous connections within the classical meridian system and theoretically predicts the existence of four additional extraordinary vessels, defining their potential confluent (master) points. In this context, the developed structural-geometric framework serves as an independent tool for predictive fundamental investigation. In Part II, the framework expands from the peripheral network architecture to the organism's central control systems. The authors introduce a proprietary conceptual electrodynamic model of the chakra system, developed based on newly identified numerical patterns of a canonical chakra attribute (the number of Tattva rays) and bioelectromagnetic modeling of multidirectional flows within the primary bioelectric channels (Ida, Pingala, and Brahma-nadi, conceptualized as a coaxial system of conductors forming the Sushumna axis). The model theoretically substantiates the mechanisms underlying the routing of specific homogeneous meridian pairs (yin–yin or yang–yang) to corresponding axial nodes (Ch1–Ch6) based on spatial polarity criteria. Furthermore, the proposed framework yields independent anatomo-morphological corollaries, demonstrating that natural lordotic and kyphotic spinal curvatures, along with the microrelief of the spinal cord, emerge as macrostructural physical manifestations of underlying electrodynamic forces and mutual Amperean repulsion. The proposed integrative framework translates empirical traditional concepts into the verifiable language of developmental biophysics, establishing a rigorous predictive foundation for systemic homeostasis modeling.