Osseous metaplasia mimicking residual tumour following neoadjuvant chemotherapy for breast carcinoma: A case report

We report the case of a 44-year-old woman who presented with a right breast lump and underwent neoadjuvant chemotherapy for biopsy-proven breast carcinoma. Post-treatment imaging suggested a poor therapeutic response and surgery was recommended following multidisciplinary team discussion. Histological examination of the resected specimen revealed no residual carcinoma. Instead, there was osseous metaplasia associated with chemotherapy-related changes. This case highlights a diagnostically challenging entity that may mimic neoplasm both clinically and radiologically. Awareness of this entity and close radiological- pathological correlation are essential to ensure accurate diagnosis and appropriate patient management.