A Novel Hybrid Endovascular Technique for Tympanojugular Paraganglioma: Flow Diversion Followed by Direct Transauricular Squid Embolization

Skull-base paragangliomas with persistent internal carotid artery (ICA) supply can be challenging to devascularize safely. We report a 17-yearold male with an Succinate Dehydrogenase Complex Iron Sulfur Subunit B (SDHB)-associated tympanojugular paraganglioma treated using a staged hybrid endovascular strategy after subtotal resection. Persistent supply from a short ICA feeder and circumferential involvement of the petrous ICA precluded safe conventional transarterial embolization. A Surpass Elite flow-diverting stent was deployed across the feeder after dual antiplatelet therapy to preserve parent-vessel patency, reduce tumour inflow, and reinforce the arterial wall. Four months later, protected direct transauricular and transcervical puncture embolization with Squid 12 was performed under intermittent ICA balloon occlusion. Marked tumor devascularization was achieved without embolic or thromboembolic complication, and definitive resection was completed without new neurological or cranial nerve deficit. This staged approach may provide a useful adjunct for selected skull-base paragangliomas with persistent ICA supply when conventional embolization carries unacceptable risk.

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Publication Details

Journal
Neurointervention
Published
2026-10-08
DOI
https://doi.org/10.5469/neuroint.2026.00857
Primary Topic
Adrenal and Paraganglionic Tumors
Type
article
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article

A Novel Hybrid Endovascular Technique for Tympanojugular Paraganglioma: Flow Diversion Followed by Direct Transauricular Squid Embolization

Rory Fairhead, Jeremy Lynch, Tufail F. Patankar, Naga Kandasamy et al.
Neurointervention
Adrenal and Paraganglionic Tumors
article

A Novel Hybrid Endovascular Technique for Tympanojugular Paraganglioma: Flow Diversion Followed by Direct Transauricular Squid Embolization

Rory Fairhead, Jeremy Lynch, Tufail F. Patankar, Naga Kandasamy, Rupert Obholzer
article en

Abstract

Skull-base paragangliomas with persistent internal carotid artery (ICA) supply can be challenging to devascularize safely. We report a 17-yearold male with an Succinate Dehydrogenase Complex Iron Sulfur Subunit B (SDHB)-associated tympanojugular paraganglioma treated using a staged hybrid endovascular strategy after subtotal resection. Persistent supply from a short ICA feeder and circumferential involvement of the petrous ICA precluded safe conventional transarterial embolization. A Surpass Elite flow-diverting stent was deployed across the feeder after dual antiplatelet therapy to preserve parent-vessel patency, reduce tumour inflow, and reinforce the arterial wall. Four months later, protected direct transauricular and transcervical puncture embolization with Squid 12 was performed under intermittent ICA balloon occlusion. Marked tumor devascularization was achieved without embolic or thromboembolic complication, and definitive resection was completed without new neurological or cranial nerve deficit. This staged approach may provide a useful adjunct for selected skull-base paragangliomas with persistent ICA supply when conventional embolization carries unacceptable risk.

Neurointervention
Guy's Hospital (GB), Royal Hospital for Neuro-disability (GB), Royal London Hospital (GB), King's College Hospital NHS Foundation Trust (GB), Queen's Hospital (GB), King's College Hospital (GB)
Openalex Percentile: Top 9%
Adrenal and Paraganglionic Tumors
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A Novel Hybrid Endovascular Technique for Tympanojugular Paraganglioma: Flow Diversion Followed by Direct Transauricular Squid Embolization — Rory Fairhead, Jeremy Lynch, et al. · Neurointervention (2026) | TGRS Research Map | TGRS