Disseminated cryptococcosis in systemic lupus erythematosus: Case report

We report a rare case of disseminated cryptococcosis gattii infection with initial central nervous system manifestations in a 28-year old male under regular treatment for systemic lupus erythematosus since 2020. He presented with headache evolving into hearing loss, hypogeusia, amblyopia and mental confusion. This case highlights the challenge of diagnosing opportunistic fungal infections in patients with chronic immuno-suppression, emphasizing how early targeted management is critical to mitigate severe neurological sequelae and reduce mortality.