Diastereo- and Regioselective Assembly of Furan-Fused Piperidine Frameworks via Rhodium-Catalyzed Intramolecular Carbonyl Ylide Cycloaddition
Abstract A new synthetic strategy for the diastereo- and regioselective construction of furano-fused piperidine and piperidinone scaffolds is described. The method proceeds via a rhodium-catalyzed intramolecular carbonyl ylide cycloaddition between readily accessible N-allylated amino aldehydes and diallyl diazo compounds.
Authors
- Vishal Agarwal (ORCID: https://orcid.org/0000-0002-1179-1704)
- Manickam Bakthadoss (ORCID: https://orcid.org/0000-0003-4184-3947)
- Sivasubramaniyan Kavikumar
- Addiga Vidya
Institutions
- Pondicherry University (IN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2026-10-08
- DOI
- https://doi.org/10.1021/acs.joc.6c01221
- Primary Topic
- Cyclopropane Reaction Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00