The Obstructive Sleep Apnea Care Ecosystem in the United States: Clinical Pathways and the Evolving Role of Otolaryngology
Obstructive sleep apnea (OSA) is a common, heterogeneous disorder managed through a multidisciplinary pathway that connects recognition, physiologic testing, treatment selection, specialty referral, insurance coverage, and longitudinal reassessment. This narrative review provides a clinically oriented, system-level overview of the adult OSA care ecosystem in the United States for an international clinical audience, with particular emphasis on the evolving role of otolaryngology. We describe the organization and complementary functions of sleep physicians, otolaryngologists, dentists, and allied health professionals. We also outline the roles of polysomnography and home sleep apnea testing, along with major therapeutic pathways including positive airway pressure, oral appliance therapy, weight management, upper-airway surgery, and neurostimulation. Otolaryngology provides an important interface between physiologic diagnosis and airway-specific treatment by integrating anatomic evaluation, sleep-state airway phenotyping, intervention selection, and post-treatment reassessment. Recent advances in neurostimulation, pharmacologic weight management, wearable and home-based monitoring, airflow analysis, and artificial intelligence are expanding opportunities for accessible and phenotype-informed care. Important challenges include underdiagnosis, treatment attrition, fragmented transitions, variable coverage, and reliance on the apnea–hypopnea index. Although health-care structures differ internationally, multidisciplinary coordination, individualized treatment selection, and longitudinal reassessment provide broadly applicable principles for developing patient-centered OSA programs.
Authors
- Xinhang Tu (ORCID: https://orcid.org/0000-0001-8765-4346)
- Yike Li (ORCID: https://orcid.org/0000-0001-8465-130X)
- Yuting Huang (ORCID: https://orcid.org/0000-0001-9986-5124)
- Alan R. Schwartz (ORCID: https://orcid.org/0000-0001-9222-3751)
- Yichen Wang (ORCID: https://orcid.org/0009-0003-9211-0919)
Institutions
- Mayo Clinic (US)
- Universidad Peruana Cayetano Heredia (PE)
- University of Michigan (US)
- Mayo Clinic in Florida (US)
- University of Pennsylvania (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Life
- Published
- 2026-10-07
- DOI
- https://doi.org/10.3390/life16101669
- Primary Topic
- Obstructive Sleep Apnea Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00