Dynamic Prototype Memory Network for Robust Multiclass Skin Lesion Diagnosis from Dermoscopic Images

Background: Automated skin lesion diagnosis from dermoscopic images is challenging because lesions of the same disease can vary substantially visually, while visually similar patterns can occur across different disease categories. This article introduces a Dynamic Prototype Memory Network (DPM-Net) for multiclass skin lesion classification. Methods: We first employ a deep visual encoder to extract discriminative feature representations from dermoscopic images. We then compare the extracted lesion embeddings with disease-specific prototypes using a similarity-based prototype assignment mechanism. To enhance the method's representational capability, we dynamically update the prototypes based on the feature distribution of the lesion samples. We incorporate a prototype diversity mechanism to prevent prototype collapse, while a prototype compactness constraint encourages lesion embeddings to remain close to the representative prototypes of their corresponding disease categories. Results: Performance validation shows improved results, with a maximum accuracy of 95.39%. Conclusion: Therefore, the proposed model integrates different components to perform automated multiclass skin lesion diagnosis from dermoscopic images.

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Publication Details

Journal
International Journal of Medical Toxicology and Forensic Medicine
Published
2026-10-06
DOI
https://doi.org/10.22037/ijmtfm.v16.53420
Primary Topic
Cutaneous Melanoma Detection and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Dynamic Prototype Memory Network for Robust Multiclass Skin Lesion Diagnosis from Dermoscopic Images

Chembian Woothukadu Thirumaran, Sharmila Varadan, Shalini Shanker, Sangeetha Tupili
International Journal of Medical Toxicology and Forensic Medicine
Cutaneous Melanoma Detection and Management
article

Dynamic Prototype Memory Network for Robust Multiclass Skin Lesion Diagnosis from Dermoscopic Images

Chembian Woothukadu Thirumaran, Sharmila Varadan, Shalini Shanker, Sangeetha Tupili
article en

Abstract

Background: Automated skin lesion diagnosis from dermoscopic images is challenging because lesions of the same disease can vary substantially visually, while visually similar patterns can occur across different disease categories. This article introduces a Dynamic Prototype Memory Network (DPM-Net) for multiclass skin lesion classification. Methods: We first employ a deep visual encoder to extract discriminative feature representations from dermoscopic images. We then compare the extracted lesion embeddings with disease-specific prototypes using a similarity-based prototype assignment mechanism. To enhance the method's representational capability, we dynamically update the prototypes based on the feature distribution of the lesion samples. We incorporate a prototype diversity mechanism to prevent prototype collapse, while a prototype compactness constraint encourages lesion embeddings to remain close to the representative prototypes of their corresponding disease categories. Results: Performance validation shows improved results, with a maximum accuracy of 95.39%. Conclusion: Therefore, the proposed model integrates different components to perform automated multiclass skin lesion diagnosis from dermoscopic images.

International Journal of Medical Toxicology and Forensic Medicine
Vel Tech Rangarajan Dr. Sagunthala R&D Institute of Science and Technology (IN)
Openalex Percentile: Top 16%
Cutaneous Melanoma Detection and Management
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Dynamic Prototype Memory Network for Robust Multiclass Skin Lesion Diagnosis from Dermoscopic Images — Chembian Woothukadu Thirumaran, Sharmila Varadan, et al. · International Journal of Medical Toxicology and Forensic Medicine (2026) | TGRS Research Map | TGRS