South Asia's cardiometabolic burden: exposomal determinants of a health transition

South Asia is facing an escalating burden of obesity, type 2 diabetes (T2D), dyslipidemia, metabolic dysfunction–associated steatotic liver disease (MASLD), and premature atherosclerotic cardiovascular disease.1–4 In 2023, high systolic blood pressure (SBP) accounted for nearly 138 million disability-adjusted life years (DALYs) and 6.27 million deaths across the Asia–Pacific region, while high body mass index, elevated LDL cholesterol, and T2D collectively contributed to more than 150 million DALYs.

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Journal
The Lancet Regional Health - Southeast Asia
Published
2026-10-07
DOI
https://doi.org/10.1016/j.lansea.2026.100881
Primary Topic
Diabetes, Cardiovascular Risks, and Lipoproteins
Type
article
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article

South Asia's cardiometabolic burden: exposomal determinants of a health transition

Anoop Misra, Yashendra Sethi
The Lancet Regional Health - Southeast Asia
Diabetes, Cardiovascular Risks, and Lipoproteins
article

South Asia's cardiometabolic burden: exposomal determinants of a health transition

Anoop Misra, Yashendra Sethi
article en

Abstract

South Asia is facing an escalating burden of obesity, type 2 diabetes (T2D), dyslipidemia, metabolic dysfunction–associated steatotic liver disease (MASLD), and premature atherosclerotic cardiovascular disease.1–4 In 2023, high systolic blood pressure (SBP) accounted for nearly 138 million disability-adjusted life years (DALYs) and 6.27 million deaths across the Asia–Pacific region, while high body mass index, elevated LDL cholesterol, and T2D collectively contributed to more than 150 million DALYs.

The Lancet Regional Health - Southeast AsiaVol. 55
Swami Vivekanand Subharti University (IN), National Diabetes Obesity and Cholesterol Foundation (IN), Diabetes Foundation (IN), Subharti Medical College (IN)
Openalex Percentile: Top 11%
Diabetes, Cardiovascular Risks, and Lipoproteins
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South Asia's cardiometabolic burden: exposomal determinants of a health transition — Anoop Misra, Yashendra Sethi · The Lancet Regional Health - Southeast Asia (2026) | TGRS Research Map | TGRS