Large language models for digital mental health: an HCI-centered scoping review
Large language models (LLMs) are rapidly reshaping digital mental health, yet how these systems are designed, used, and evaluated remains poorly characterized. We conducted an HCI-centered scoping review of 84 studies examining mental health tasks, stakeholders, interaction paradigms, foundation models, evaluation methods, and outcome measurement. Counseling and support and self-help and well-being accounted for 73.8% of studies, while clinician support and crisis and risk support remained uncommon. Mixed-methods user studies predominated (42.9%), with only three randomized controlled trials and eight studies classified as longitudinal or field evaluations. Technical and response performance was assessed in 81.0% of studies, compared with 29.8% assessing mental health symptoms and clinical outcomes and 7.1% including longitudinal follow-up. Outcome profiles differed across intended tasks. Building on these findings and established evaluation guidance, we propose a task-oriented framework aligning evaluation domains, measurement approaches, and assessment timing with intended use.
Authors
- Yu Hou (ORCID: https://orcid.org/0009-0009-7184-6592)
- Kai Yu (ORCID: https://orcid.org/0000-0002-9760-7751)
- Zaifu Zhan (ORCID: https://orcid.org/0009-0007-5973-2432)
- Min Zeng (ORCID: https://orcid.org/0009-0007-8289-6419)
- Chao Zeng
- Shuang Zhou
- Rui Zhang
- Mingquan Lin
- Duzhen Zhang
Institutions
- University of Minnesota (US)
- Mohamed bin Zayed University of Artificial Intelligence (AE)
Publication Details
- Journal
- npj Digital Medicine
- Published
- 2026-10-07
- DOI
- https://doi.org/10.1038/s41746-026-03317-7
- Primary Topic
- Digital Mental Health Interventions
- Type
- article
- Field-Weighted Citation Impact
- 0.00