Direct Oral Anticoagulant–Calibrated Heparin LRT Assay as a Rapid Alternative to an Anti‐Factor Xa Assay for Measuring Apixaban, Edoxaban, and Rivaroxaban in Patients With Non‐Valvular Atrial Fibrillation

The data that support the findings of this study are openly available in Jin-Yeong Han at ORCID, reference number ORCID: 0000-0003-0280-2739. Figure S1: Passing–Bablok regression of DOAC concentrations measured with the DOAC-calibrated Heparin LRT reagent (Y axis) against the DiXaI reagent (X axis) for apixaban (A–C), edoxaban (D–F), and rivaroxaban (G–I) at trough, peak, and all sampling points combined. The solid line represents the regression line and the dotted line indicates the line of identity (Y = X). DOAC, direct oral anticoagulants; DiXaI, direct factor Xa inhibitor reagent; LRT, liquid reagent technology. Table S1: Baseline characteristics and reagent lower limits of quantification by DOAC. Both reagents were calibrated with drug-specific DOAC calibrators. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

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Publication Details

Journal
International Journal of Laboratory Hematology
Published
2026-10-06
DOI
https://doi.org/10.1111/ijlh.70257
Primary Topic
Atrial Fibrillation Management and Outcomes
Type
article
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article

Direct Oral Anticoagulant–Calibrated Heparin LRT Assay as a Rapid Alternative to an Anti‐Factor Xa Assay for Measuring Apixaban, Edoxaban, and Rivaroxaban in Patients With Non‐Valvular Atrial Fibrillation

Jin‐Yeong Han, Kwang‐Sook Woo, Kyunghee Lim, Dae‐Hyun Kim et al.
International Journal of Laboratory Hematology
Atrial Fibrillation Management and Outcomes
article

Direct Oral Anticoagulant–Calibrated Heparin LRT Assay as a Rapid Alternative to an Anti‐Factor Xa Assay for Measuring Apixaban, Edoxaban, and Rivaroxaban in Patients With Non‐Valvular Atrial Fibrillation

Jin‐Yeong Han, Kwang‐Sook Woo, Kyunghee Lim, Dae‐Hyun Kim, Jong Sung Park
article en

Abstract

The data that support the findings of this study are openly available in Jin-Yeong Han at ORCID, reference number ORCID: 0000-0003-0280-2739. Figure S1: Passing–Bablok regression of DOAC concentrations measured with the DOAC-calibrated Heparin LRT reagent (Y axis) against the DiXaI reagent (X axis) for apixaban (A–C), edoxaban (D–F), and rivaroxaban (G–I) at trough, peak, and all sampling points combined. The solid line represents the regression line and the dotted line indicates the line of identity (Y = X). DOAC, direct oral anticoagulants; DiXaI, direct factor Xa inhibitor reagent; LRT, liquid reagent technology. Table S1: Baseline characteristics and reagent lower limits of quantification by DOAC. Both reagents were calibrated with drug-specific DOAC calibrators. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

International Journal of Laboratory Hematology
Dong-A University (KR)
Openalex Percentile: Top 11%
Atrial Fibrillation Management and Outcomes
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Direct Oral Anticoagulant–Calibrated Heparin LRT Assay as a Rapid Alternative to an Anti‐Factor Xa Assay for Measuring Apixaban, Edoxaban, and Rivaroxaban in Patients With Non‐Valvular Atrial Fibrillation — Jin‐Yeong Han, Kwang‐Sook Woo, et al. · International Journal of Laboratory Hematology (2026) | TGRS Research Map | TGRS