MiKid-QA: construction and performance evaluation of a paediatric myopia education question-answering model
Background The surging prevalence of paediatric myopia has overwhelmed clinical education services. While general-purpose large language models (LLMs) are increasingly used for medical information, they often lack the domain-specific precision required for specialised care. This study aimed to develop and evaluate Myopia in Kids Question-Answering (MiKid-QA), a paediatric myopia education question-answering model fine-tuned to support standardised patient education. Methods We conducted a cross-sectional evaluation study. MiKid-QA was developed by fine-tuning the Qwen2.5-32B model using low-rank adaptation (LoRA) on curated professional datasets (2015–2025), including textbooks and expert consensus. Performance was assessed against DeepSeek and GPT-4 through a multicentre, single-blind expert evaluation of 25 standardised clinical scenarios. A panel of specialists rated responses across five dimensions (correctness, completeness, readability, helpfulness and safety) using a 5-point Likert scale. Results MiKid-QA demonstrated superior automated performance compared with its base model (Bilingual Evaluation Understudy: 0.1423 vs 0.0967). In expert evaluations, MiKid-QA achieved significantly higher scores for correctness (4.43±0.63) and safety (4.38±0.59) compared with DeepSeek and GPT-4 (all p<0.001). While completeness and helpfulness were comparable (p>0.05), MiKid-QA produced more concise responses and lower reading difficulty than GPT-4 (p<0.001), suggesting a potentially favourable balance between information accuracy and patient accessibility in standardised educational scenarios. Conclusion Specialised fine-tuning on curated myopia-related datasets was associated with higher expert-rated correctness and safety in standardised myopia education scenarios. MiKid-QA may serve as an auxiliary educational tool to support patient communication in myopia care, although further external validation and prospective clinical studies are required before clinical deployment.
Authors
- Bei Du (ORCID: https://orcid.org/0000-0002-0947-1541)
- 鹿大千
- X. J. Zhang (ORCID: https://orcid.org/0009-0001-2753-8332)
- Ruihua Wei (ORCID: https://orcid.org/0000-0002-9708-0355)
- Jingtao Yu (ORCID: https://orcid.org/0009-0001-1916-0384)
- Jing Yang (ORCID: https://orcid.org/0000-0002-9216-4744)
- Zixun Wang
- Xueshuo Xie
- Yabin Hu
- Tingyu Zhang
- Liqin Huang (ORCID: https://orcid.org/0009-0000-4554-5483)
- Xu Yan
- Xiaoxue Hu
- Yifan Li (ORCID: https://orcid.org/0009-0000-2298-4475)
- Jun Zhou
Institutions
- Beijing Tongren Hospital (CN)
- Hong Kong Polytechnic University (HK)
- Sun Yat-sen University (CN)
- Capital Medical University (CN)
- Nankai University (CN)
- Shanghai Ninth People's Hospital (CN)
- Han Dan City Eye Hospital - The Third Hospital of Handan (CN)
- Wuhan Children's Hospital (CN)
- Tianjin Medical University Eye Hospital (CN)
- State Key Laboratory of Ophthalmology
- Zhongshan Ophthalmic Center, Sun Yat-sen University
- Tianjin Medical University (CN)
Publication Details
- Journal
- British Journal of Ophthalmology
- Published
- 2026-10-06
- DOI
- https://doi.org/10.1136/bjo-2026-329816
- Primary Topic
- Artificial Intelligence in Healthcare and Education
- Type
- article
- Field-Weighted Citation Impact
- 0.00