Securing the oligonucleotide supply chain: addressing raw material risks, environmental pressures, and geopolitical factors
The rapid growth of the oligonucleotide therapeutics field has highlighted how vulnerable the supporting supply chain can be. As the demand increases, manufacturers must face constraints in raw materials, increasing environmental pressures, and a shifting geopolitical landscape. Companies must adopt strategic measures to ensure an adequate supply of raw materials. Nucleic Acid Insights brought together a panel of experts to discuss the key challenges and emerging solutions in this space. The discussion covers how the industry can build supply chain resilience, mitigate risk, and create sustainable supply networks for oligonucleotide therapeutics.
Authors
- Louis J. Diorazio (ORCID: https://orcid.org/0000-0001-8017-9167)
- Subhadeep Roy
- Dennis Rhodes
Institutions
- AstraZeneca (United Kingdom) (GB)
- Ionis Pharmaceuticals (United States) (US)
Publication Details
- Journal
- Nucleic Acid Insights
- Published
- 2026-10-05
- DOI
- https://doi.org/10.18609/nuc.2026.070
- Primary Topic
- Supply Chain Resilience and Risk Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00