Securing the oligonucleotide supply chain: addressing raw material risks, environmental pressures, and geopolitical factors

The rapid growth of the oligonucleotide therapeutics field has highlighted how vulnerable the supporting supply chain can be. As the demand increases, manufacturers must face constraints in raw materials, increasing environmental pressures, and a shifting geopolitical landscape. Companies must adopt strategic measures to ensure an adequate supply of raw materials. Nucleic Acid Insights brought together a panel of experts to discuss the key challenges and emerging solutions in this space. The discussion covers how the industry can build supply chain resilience, mitigate risk, and create sustainable supply networks for oligonucleotide therapeutics.

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Publication Details

Journal
Nucleic Acid Insights
Published
2026-10-05
DOI
https://doi.org/10.18609/nuc.2026.070
Primary Topic
Supply Chain Resilience and Risk Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Securing the oligonucleotide supply chain: addressing raw material risks, environmental pressures, and geopolitical factors

Louis J. Diorazio, Subhadeep Roy, Dennis Rhodes
Nucleic Acid Insights
Supply Chain Resilience and Risk Management
article

Securing the oligonucleotide supply chain: addressing raw material risks, environmental pressures, and geopolitical factors

Louis J. Diorazio, Subhadeep Roy, Dennis Rhodes
article en

Abstract

The rapid growth of the oligonucleotide therapeutics field has highlighted how vulnerable the supporting supply chain can be. As the demand increases, manufacturers must face constraints in raw materials, increasing environmental pressures, and a shifting geopolitical landscape. Companies must adopt strategic measures to ensure an adequate supply of raw materials. Nucleic Acid Insights brought together a panel of experts to discuss the key challenges and emerging solutions in this space. The discussion covers how the industry can build supply chain resilience, mitigate risk, and create sustainable supply networks for oligonucleotide therapeutics.

Nucleic Acid InsightsVol. 3(9)
AstraZeneca (United Kingdom) (GB), Ionis Pharmaceuticals (United States) (US)
Openalex Percentile: Top 8%
Supply Chain Resilience and Risk Management
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Securing the oligonucleotide supply chain: addressing raw material risks, environmental pressures, and geopolitical factors — Louis J. Diorazio, Subhadeep Roy, et al. · Nucleic Acid Insights (2026) | TGRS Research Map | TGRS