Composite homograft in a pediatric patient with prosthetic aortic valve endocarditis

A composite aortic homograft was used in a 14-year-old patient with prosthetic aortic valve endocarditis. There were severe prosthesis-patient mismatch and active infection confirmed by Staphylococcus aureus isolation. Redo surgery implied removal of infected prosthesis, debridement and implantation of a cryopreserved composite homograft. Postoperative period was characterized by normal homograft function, relief of infection and significant clinical improvement without the need for lifelong anticoagulation. Homograft demonstrated high efficacy in complex clinical scenario.

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Publication Details

Journal
Russian Journal of Cardiology and Cardiovascular Surgery
Published
2026-10-06
DOI
https://doi.org/10.17116/kardio20261905179
Primary Topic
Infective Endocarditis Diagnosis and Management
Type
article
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article

Composite homograft in a pediatric patient with prosthetic aortic valve endocarditis

Roman Nikolaevich Komarov, Maxim I. Tkachev, Georgy A. Varlamov, Nima-Surun T. Choibsonov
Russian Journal of Cardiology and Cardiovascular Surgery
Infective Endocarditis Diagnosis and Management
article

Composite homograft in a pediatric patient with prosthetic aortic valve endocarditis

Roman Nikolaevich Komarov, Maxim I. Tkachev, Georgy A. Varlamov, Nima-Surun T. Choibsonov
article en

Abstract

A composite aortic homograft was used in a 14-year-old patient with prosthetic aortic valve endocarditis. There were severe prosthesis-patient mismatch and active infection confirmed by Staphylococcus aureus isolation. Redo surgery implied removal of infected prosthesis, debridement and implantation of a cryopreserved composite homograft. Postoperative period was characterized by normal homograft function, relief of infection and significant clinical improvement without the need for lifelong anticoagulation. Homograft demonstrated high efficacy in complex clinical scenario.

Russian Journal of Cardiology and Cardiovascular SurgeryVol. 19(5)
Sechenov University (RU)
Openalex Percentile: Top 11%
Infective Endocarditis Diagnosis and Management
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Composite homograft in a pediatric patient with prosthetic aortic valve endocarditis — Roman Nikolaevich Komarov, Maxim I. Tkachev, et al. · Russian Journal of Cardiology and Cardiovascular Surgery (2026) | TGRS Research Map | TGRS