Critical windows: timing of child maltreatment exposure and adult mental health

Abstract Background Despite being recognized as the leading risk factor for mental disorders, child maltreatment (CM) remains insufficiently understood regarding type and timing of exposure. This study examines which developmental periods of exposure to CM subtypes are most strongly associated with adult mental disorders in women and men. Methods Data from a German survey study from 2021 was used. The sample included N = 1,278 women [51.8%] ( M age = 50.3; SD = 17.6) and N = 1,188 men [48.2%] ( M age = 51.1; SD = 17.6). CM was assessed using the ISPCAN Child Abuse Screening Tools Retrospective version questionnaire. Conditioned Random Forest regression analyses were applied to examine the relevance of type and timing of CM for internalising [IMD] and externalising mental disorders [EMD] in adulthood. SHapley Additive exPlanations analyses were performed as post-hoc tests. Results Timing of exposure to emotional abuse was most strongly associated with IMD; for women between ages 10–16 (variable importance [VI] ranging from 0.255 to 1.014), and for men ages 13 and 14 (VI: 0.349 and VI: 0.504). For men, EMD were most closely linked to emotional abuse between ages 10–16 (VI: 0.174–0.968), for women to exposure to sexual abuse between ages 13–15 (VI: 0.136–0.331) and neglect between ages 11–17 (VI: 0.098–0.331). Conclusion Distinct developmental windows of vulnerability to varying subtypes of CM shape adult mental health differently in women and men. Considering timing of subtypes of CM may enhance diagnosis and prevention strategies aimed at reducing lifetime mental health risks.

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Publication Details

Journal
Child and Adolescent Psychiatry and Mental Health
Published
2026-10-06
DOI
https://doi.org/10.1186/s13034-026-01188-0
Primary Topic
Child Abuse and Trauma
Type
article
Field-Weighted Citation Impact
0.00
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article

Critical windows: timing of child maltreatment exposure and adult mental health

Elmar Brähler, Daniëlle Otten, Vera Clemens, Andreas Jud et al.
Child and Adolescent Psychiatry and Mental Health
Child Abuse and Trauma
article

Critical windows: timing of child maltreatment exposure and adult mental health

Elmar Brähler, Daniëlle Otten, Vera Clemens, Andreas Jud, Inga Schalinski, Jörg M. Fegert
article en

Abstract

Abstract Background Despite being recognized as the leading risk factor for mental disorders, child maltreatment (CM) remains insufficiently understood regarding type and timing of exposure. This study examines which developmental periods of exposure to CM subtypes are most strongly associated with adult mental disorders in women and men. Methods Data from a German survey study from 2021 was used. The sample included N = 1,278 women [51.8%] ( M age = 50.3; SD = 17.6) and N = 1,188 men [48.2%] ( M age = 51.1; SD = 17.6). CM was assessed using the ISPCAN Child Abuse Screening Tools Retrospective version questionnaire. Conditioned Random Forest regression analyses were applied to examine the relevance of type and timing of CM for internalising [IMD] and externalising mental disorders [EMD] in adulthood. SHapley Additive exPlanations analyses were performed as post-hoc tests. Results Timing of exposure to emotional abuse was most strongly associated with IMD; for women between ages 10–16 (variable importance [VI] ranging from 0.255 to 1.014), and for men ages 13 and 14 (VI: 0.349 and VI: 0.504). For men, EMD were most closely linked to emotional abuse between ages 10–16 (VI: 0.174–0.968), for women to exposure to sexual abuse between ages 13–15 (VI: 0.136–0.331) and neglect between ages 11–17 (VI: 0.098–0.331). Conclusion Distinct developmental windows of vulnerability to varying subtypes of CM shape adult mental health differently in women and men. Considering timing of subtypes of CM may enhance diagnosis and prevention strategies aimed at reducing lifetime mental health risks.

Child and Adolescent Psychiatry and Mental Health
Johannes Gutenberg University Mainz (DE), ZHAW Zurich University of Applied Sciences (CH), Universität der Bundeswehr München (DE), University Medical Center of the Johannes Gutenberg University Mainz (DE), University Hospital Ulm (DE), Deutsches Zentrum für Psychische Gesundheit (DE), University of Rostock (DE)
Openalex Percentile: Top 7%
Child Abuse and Trauma
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