Outside Front Cover: Rational Molecular Design to Improve Digital Polymer Readout in Aerolysin‐Based Nanopore Sequencing
The cover depicts polymers as colourful molecular “beads” threading through an aerolysin nanopore embedded in a lipid membrane. Rationally designed monomers, represented by distinct colours and digital symbols, produce characteristic translocation signals. By tuning polymer architecture and pore interactions, molecular structures can be translated into reliable digital information at the single-molecule level. More In the Research Article e1446100, Matteo Dal Peraro, Jean-François Lutz, and co-workers.
Authors
- Jean‐François Lutz (ORCID: https://orcid.org/0000-0002-3893-2458)
- Juan F. Bada Juarez (ORCID: https://orcid.org/0000-0002-1337-6424)
- Chan Cao (ORCID: https://orcid.org/0000-0003-2592-0690)
- Zhaozheng Yang (ORCID: https://orcid.org/0000-0001-7075-3639)
- María J. Marcaida (ORCID: https://orcid.org/0000-0003-0663-5309)
- Matteo Dal Peraro (ORCID: https://orcid.org/0000-0002-2973-3975)
- Alissa Agerova (ORCID: https://orcid.org/0009-0002-9399-4675)
- Georgette Obeid (ORCID: https://orcid.org/0009-0005-7418-7458)
- Davide Cois (ORCID: https://orcid.org/0009-0001-9730-8794)
- Thomas R. Bryner (ORCID: https://orcid.org/0009-0001-8910-4134)
Institutions
- University of Geneva (CH)
- Centre National de la Recherche Scientifique (FR)
- Institut de Science et d'Ingénierie Supramoléculaires (FR)
- École Polytechnique Fédérale de Lausanne (CH)
- Université de Strasbourg (FR)
Publication Details
- Journal
- Angewandte Chemie International Edition
- Published
- 2026-10-05
- DOI
- https://doi.org/10.1002/anie.2026-m0210095400
- Primary Topic
- Nanopore and Nanochannel Transport Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00