Comparing three approaches to delirium identification in older patients presenting to the emergency department

Abstract Introduction Early identification of hospitalised patients with or at risk for delirium is important to treat patients adequately. The aim of this study is to compare three approaches to delirium identification for identifying patients being at risk for or with a delirium during hospitalisation in a cohort of older patients presenting to the emergency department, including retrospectively extracted indicators of delirium based on prehospital care notes, by risk assessment (VMS), and screening instrument (4AT). Methods A single-centre cohort study was conducted with the use of data from patients 70 years and older from Acutelines, a hospital-based biobank. extended with extraction of documented prehospital indicators based on prehospital care notes and a hospital chart-based review as a reference standard to determine whether patients experienced delirium during hospitalisation. We compared the different approaches by calculating standard performance measures (e.g. sensitivity, specificity, and predictive values). Results Data of 655 patients were included. Median age was 76 years, and 407 (62%) were male. During hospitalisation, 146 patients (22%) were identified as having a delirium. The positive likelihood ratios were 5.54 for the documented prehospital indicators, 1.55 for the VMS risk assessment, and 2.39 for the 4AT screening. Conclusion All three approaches, the documented prehospital indicators, the VMS risk assessment, and 4AT screening, are associated with delirium during hospitalisation. The documented prehospital indicators could be of added value, and we see this as a starting point for research into how the prehospital information could be used in the acute care pathway for older patients with or at risk for delirium.

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Publication Details

Journal
European Geriatric Medicine
Published
2026-10-05
DOI
https://doi.org/10.1007/s41999-026-01612-w
Primary Topic
Intensive Care Unit Cognitive Disorders
Type
article
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article

Comparing three approaches to delirium identification in older patients presenting to the emergency department

Monika Trzpis, Barbara C. Van Munster, Maaike A. Pouw, Carolien J. Jansen et al.
European Geriatric Medicine
Intensive Care Unit Cognitive Disorders
article

Comparing three approaches to delirium identification in older patients presenting to the emergency department

Monika Trzpis, Barbara C. Van Munster, Maaike A. Pouw, Carolien J. Jansen, Eline G. Haan
article en

Abstract

Abstract Introduction Early identification of hospitalised patients with or at risk for delirium is important to treat patients adequately. The aim of this study is to compare three approaches to delirium identification for identifying patients being at risk for or with a delirium during hospitalisation in a cohort of older patients presenting to the emergency department, including retrospectively extracted indicators of delirium based on prehospital care notes, by risk assessment (VMS), and screening instrument (4AT). Methods A single-centre cohort study was conducted with the use of data from patients 70 years and older from Acutelines, a hospital-based biobank. extended with extraction of documented prehospital indicators based on prehospital care notes and a hospital chart-based review as a reference standard to determine whether patients experienced delirium during hospitalisation. We compared the different approaches by calculating standard performance measures (e.g. sensitivity, specificity, and predictive values). Results Data of 655 patients were included. Median age was 76 years, and 407 (62%) were male. During hospitalisation, 146 patients (22%) were identified as having a delirium. The positive likelihood ratios were 5.54 for the documented prehospital indicators, 1.55 for the VMS risk assessment, and 2.39 for the 4AT screening. Conclusion All three approaches, the documented prehospital indicators, the VMS risk assessment, and 4AT screening, are associated with delirium during hospitalisation. The documented prehospital indicators could be of added value, and we see this as a starting point for research into how the prehospital information could be used in the acute care pathway for older patients with or at risk for delirium.

European Geriatric Medicine
University Medical Center Groningen (NL), University of Groningen (NL), Martini Ziekenhuis (NL), Ziekenhuis Nij Smellinghe (NL)
Openalex Percentile: Top 10%
Intensive Care Unit Cognitive Disorders
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