Recent Progress in Skin Bioelectronics for Electrophysiological Monitoring

ABSTRACT The acquisition of high‐quality electrophysiological signals can provide comprehensive information in disease diagnosis, athletic training, human‐computer interaction, and human healthcare, which plays an important role in improving the quality of life, boosting the development of wearable bioelectronics. This review addresses recent progress in skin bioelectronics for electrophysiological signal monitoring and its applications. First, the crucial properties of functional electronic materials used for bioelectrode fabrication during the signal acquisition are addressed. Then the bioelectrode/device and its fabrication techniques are discussed in terms of the material characteristics. Subsequently, the important components of the epidermal bioelectronics system, including the multichannel bioelectrode array, stable electrical interfaces, and miniaturized signal processing platform, are described respectively, which are further integrated to form a wearable electronic device for high‐fidelity electrophysiological signal monitoring. Next, the applications of fully integrated skin bioelectronics are summarized. With the help of advanced artificial intelligence, intelligent sensing devices are further developed, achieving new breakthroughs in the medical field and intelligent machine control. Finally, the conclusion, challenges and future opportunities of on‐skin bioelectronics for epidermal electrophysiology are discussed.