Primary Varicella Infection Presenting as Kaposi Varicelliform Eruption in an Unimmunized Infant With Severe Atopic Dermatitis: A Case Report

Learning Points Kaposi varicelliform eruption is classically associated with herpes simplex virus but may rarely occur secondary to primary varicella‐zoster virus infection. Children with poorly controlled atopic dermatitis are at increased risk because of impaired skin barrier function. Clinical morphology and distribution are necessary to make the initial diagnosis of Kaposi varicelliform eruption, with a positive VZV PCR confirming the pathogenic source. Early PCR confirmation and prompt antiviral therapy are essential to reduce the risk of serious complications. Routine varicella immunization substantially reduces severe varicella disease and remains an important strategy for preventing complications of primary VZV infection.

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Publication Details

Journal
Journal of Paediatrics and Child Health
Published
2026-10-03
DOI
https://doi.org/10.1111/jpc.70608
Primary Topic
Herpesvirus Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Primary Varicella Infection Presenting as Kaposi Varicelliform Eruption in an Unimmunized Infant With Severe Atopic Dermatitis: A Case Report

Bo Borch‐Christensen, Jaron A. Smith, Vanessa Gildenstern, Anjali Agrawal
Journal of Paediatrics and Child Health
Herpesvirus Infections and Treatments
article

Primary Varicella Infection Presenting as Kaposi Varicelliform Eruption in an Unimmunized Infant With Severe Atopic Dermatitis: A Case Report

Bo Borch‐Christensen, Jaron A. Smith, Vanessa Gildenstern, Anjali Agrawal
article en

Abstract

Learning Points Kaposi varicelliform eruption is classically associated with herpes simplex virus but may rarely occur secondary to primary varicella‐zoster virus infection. Children with poorly controlled atopic dermatitis are at increased risk because of impaired skin barrier function. Clinical morphology and distribution are necessary to make the initial diagnosis of Kaposi varicelliform eruption, with a positive VZV PCR confirming the pathogenic source. Early PCR confirmation and prompt antiviral therapy are essential to reduce the risk of serious complications. Routine varicella immunization substantially reduces severe varicella disease and remains an important strategy for preventing complications of primary VZV infection.

Journal of Paediatrics and Child Health
Phoenix Children's Hospital (US)
Openalex Percentile: Top 11%
Herpesvirus Infections and Treatments
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Primary Varicella Infection Presenting as Kaposi Varicelliform Eruption in an Unimmunized Infant With Severe Atopic Dermatitis: A Case Report — Bo Borch‐Christensen, Jaron A. Smith, et al. · Journal of Paediatrics and Child Health (2026) | TGRS Research Map | TGRS