P2-ALTLIFE: v2.0 Evidence-Mapping Proposal for Alternative Biochemistry

Documentation-only v2.0 evidence-mapping proposal in the existing P2-ALTLIFE version family. This newly original English PDF sets out distinct evidence columns for synthesis, stability, templating, copying, dependence on supplied enzymes or reagents, metabolism, autonomous reproduction, evolution and natural occurrence. A worked synthetic example shows why polymerase-assisted XNA copying does not establish autonomous life. No primary-source candidate matrix is populated in this v2 workpack, and no new wet-lab observation, natural occurrence or biological validation is claimed. Only this explanatory PDF is uploaded; no earlier code, archive, data or third-party figure is included. Earlier version: https://doi.org/10.5281/zenodo.22151674 . CC BY 4.0 applies solely to this newly original PDF, not to earlier software or cited works. Computational and AI assistance is disclosed; Riccardo Giudici is responsible for the presentation as an independent systems orchestrator. No institutional endorsement is claimed.

Authors

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-10-03
DOI
https://doi.org/10.5281/zenodo.23112871
Primary Topic
Origins and Evolution of Life
Type
preprint
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P2-ALTLIFE: v2.0 Evidence-Mapping Proposal for Alternative Biochemistry

Riccardo Giudici
Zenodo (CERN European Organization for Nuclear Research)
Origins and Evolution of Life
preprint

P2-ALTLIFE: v2.0 Evidence-Mapping Proposal for Alternative Biochemistry

Riccardo Giudici
preprint en

Abstract

Documentation-only v2.0 evidence-mapping proposal in the existing P2-ALTLIFE version family. This newly original English PDF sets out distinct evidence columns for synthesis, stability, templating, copying, dependence on supplied enzymes or reagents, metabolism, autonomous reproduction, evolution and natural occurrence. A worked synthetic example shows why polymerase-assisted XNA copying does not establish autonomous life. No primary-source candidate matrix is populated in this v2 workpack, and no new wet-lab observation, natural occurrence or biological validation is claimed. Only this explanatory PDF is uploaded; no earlier code, archive, data or third-party figure is included. Earlier version: https://doi.org/10.5281/zenodo.22151674 . CC BY 4.0 applies solely to this newly original PDF, not to earlier software or cited works. Computational and AI assistance is disclosed; Riccardo Giudici is responsible for the presentation as an independent systems orchestrator. No institutional endorsement is claimed.

Zenodo (CERN European Organization for Nuclear Research)
Origins and Evolution of Life
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P2-ALTLIFE: v2.0 Evidence-Mapping Proposal for Alternative Biochemistry — Riccardo Giudici · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS