Allium sativum , a Natural and Pharmaco‐Remedial Panacea for Entero‐Gastritis, Antibiocidal/Dysbiogenesis, and Systemic Health Relevance
ABSTRACT Arising from the emergence of diverse difficult‐to‐treat health cases, alterative‐therapeutic strategies have become a potential way forward for management/control. In traditional Chinese medicine (TCM), various plant materials have been sourced as alterative‐therapeutic resources due to their richness in bioactive components and their cell‐effecting potential. One such sourced plant is Allium sativum , with underreported gastrointestinal health implications. This study determines the natural and pharmaco‐remedial panacea for enterogastritis, antibiocidal/dysbiogenesis, and systemic health concerns of Allium sativum . Forty male white/albino rats aged between 12 and 18 weeks were used as experimental animals (EAs). Briefly, apparently healthy EAs were acclimatized and euthanized, and stool samples were collected. Standard microbiological studies, tissue histology, and biochemical analysis were conducted within the study period after treatment with various increasing concentrations of garlic extract. Distinct antibacterial clear zones of inhibition and a significant ( p > 0.01) effect were observed for gut coliform count, revealing antibiocidal/dysbiogenesis and systemic health relevance, with impact on hematological and hepatocyte indices after treatment dosage. An investigation into the optimal dosage and concentration of garlic should be carefully observed to achieve effective systemic health benefits, gastrointestinal health, and total well‐being, especially in both modern Chinese medicine (MCM) and TCM for immune boosting, respiratory‐health concerns, cholera/dysentery, etc., to improve systemic health within a specific time range.
Authors
- Oghenenyore Andy Ohwokevwo (ORCID: https://orcid.org/0000-0003-2802-543X)
- Bright Esegbuyota Igere (ORCID: https://orcid.org/0000-0003-0059-4593)
- Anthony Jude Anozie
- Patience O. Adomi
Institutions
- Delta State University (NG)
- Delta State Polytechnic Ogwashi-Uku (NG)
- Delta State University (US)
Publication Details
- Journal
- AgriFood Journal of Agricultural Products for Food
- Published
- 2026-10-03
- DOI
- https://doi.org/10.1002/agf2.70037
- Primary Topic
- Garlic and Onion Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00