Design and Implementation of an Inline Coater for Solvent-Based Polyurethane Microelectrode Insulation

Abstract The growing use of microelectrodes in medical technology requires scalable manufacturing processes for high-quality, reproducible, and biocompatible insulation layers. This need is particularly evident in advanced neuroprosthetic systems for upper-limb amputees, where reliable neural and muscular interfaces are essential for intuitive control of bionic prostheses. Current developments aim to integrate electrode-equipped, osseointegrated implants capable of bidirectional communication with the neuromuscular system. Conventional batch coating techniques for microelectrodes often struggle to achieve consistent coating properties at industrial scale. In this work, we present the design and implementation of an inline coater for the continuous deposition of solvent-based polyurethane layers on fine metallic wires. The automated system enables controlled withdrawal of wires from a polymer solution, providing precise adjustment of coating thickness through key process parameters such as solution composition and withdrawal speed. First coating trials on microwires demonstrated homogeneous polyurethane insulation layers. Confocal laser scanning microscopy confirmed that the resulting film thickness correlates predictably with the selected process parameters, highlighting the potential of this approach for scalable production of durable and biocompatible wire insulation for medical applications.

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Publication Details

Journal
Current Directions in Biomedical Engineering
Published
2026-10-01
DOI
https://doi.org/10.1515/cdbme-2026-0230
Primary Topic
Neuroscience and Neural Engineering
Type
article
Field-Weighted Citation Impact
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article

Design and Implementation of an Inline Coater for Solvent-Based Polyurethane Microelectrode Insulation

Alexander Thiesen, Sylvia Pfensig, Stefan Siewert, Thomas Reske et al.
Current Directions in Biomedical Engineering
Neuroscience and Neural Engineering
article

Design and Implementation of an Inline Coater for Solvent-Based Polyurethane Microelectrode Insulation

Alexander Thiesen, Sylvia Pfensig, Stefan Siewert, Thomas Reske, Klaus‐Peter Schmitz, Lucas Tetzlaff, Henk van de Meent
article en

Abstract

Abstract The growing use of microelectrodes in medical technology requires scalable manufacturing processes for high-quality, reproducible, and biocompatible insulation layers. This need is particularly evident in advanced neuroprosthetic systems for upper-limb amputees, where reliable neural and muscular interfaces are essential for intuitive control of bionic prostheses. Current developments aim to integrate electrode-equipped, osseointegrated implants capable of bidirectional communication with the neuromuscular system. Conventional batch coating techniques for microelectrodes often struggle to achieve consistent coating properties at industrial scale. In this work, we present the design and implementation of an inline coater for the continuous deposition of solvent-based polyurethane layers on fine metallic wires. The automated system enables controlled withdrawal of wires from a polymer solution, providing precise adjustment of coating thickness through key process parameters such as solution composition and withdrawal speed. First coating trials on microwires demonstrated homogeneous polyurethane insulation layers. Confocal laser scanning microscopy confirmed that the resulting film thickness correlates predictably with the selected process parameters, highlighting the potential of this approach for scalable production of durable and biocompatible wire insulation for medical applications.

Current Directions in Biomedical EngineeringVol. 12(1)
Institute for ImplantTechnology and Biomaterials (DE)
Openalex Percentile: Top 17%
Neuroscience and Neural Engineering
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