Mixed Neuroendocrine—Non‐Neuroendocrine Neoplasm ( MiNEN ) of the Gallbladder. A Case Report From a Low‐Resource Setting

ABSTRACT Mixed neuroendocrine–non‐neuroendocrine neoplasms (MiNENs) of the gallbladder are exceedingly rare entities. We report a case of a 35‐year‐old female with a palpable right hypochondrial mass. Imaging demonstrated a large polypoid gallbladder lesion with periportal lymphadenopathy. The patient underwent open cholecystectomy with lymphadenectomy. Histopathology and immunohistochemistry revealed a MiNEN. At 12‐month follow‐up, she remained free of recurrence without any adjuvant chemotherapy.

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Journal
Clinical Case Reports
Published
2026-09-29
DOI
https://doi.org/10.1002/ccr3.73652
Primary Topic
Neuroendocrine Tumor Research Advances
Type
article
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article

Mixed Neuroendocrine—Non‐Neuroendocrine Neoplasm ( MiNEN ) of the Gallbladder. A Case Report From a Low‐Resource Setting

Beenish Sabir, Muhammad Farhan, Muhammad Imran, Zohaib Ahmed et al.
Clinical Case Reports
Neuroendocrine Tumor Research Advances
article

Mixed Neuroendocrine—Non‐Neuroendocrine Neoplasm ( MiNEN ) of the Gallbladder. A Case Report From a Low‐Resource Setting

Beenish Sabir, Muhammad Farhan, Muhammad Imran, Zohaib Ahmed, Nadira Mamoon, Rahmat Gul Omarzai, Muhammad Asim, Shahid Hussain, Farheen Khan, Khalil Ahmad
article en

Abstract

ABSTRACT Mixed neuroendocrine–non‐neuroendocrine neoplasms (MiNENs) of the gallbladder are exceedingly rare entities. We report a case of a 35‐year‐old female with a palpable right hypochondrial mass. Imaging demonstrated a large polypoid gallbladder lesion with periportal lymphadenopathy. The patient underwent open cholecystectomy with lymphadenectomy. Histopathology and immunohistochemistry revealed a MiNEN. At 12‐month follow‐up, she remained free of recurrence without any adjuvant chemotherapy.

Clinical Case ReportsVol. 14(10)
Rawalpindi Medical University (PK), Government of Pakistan (PK), Nangarhar University (AF), Shifa International Hospital (PK)
Openalex Percentile: Top 11%
Neuroendocrine Tumor Research Advances
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Mixed Neuroendocrine—Non‐Neuroendocrine Neoplasm ( MiNEN ) of the Gallbladder. A Case Report From a Low‐Resource Setting — Beenish Sabir, Muhammad Farhan, et al. · Clinical Case Reports (2026) | TGRS Research Map | TGRS