Alveolar Hemorrhage in Weil\'s Disease and Coexisting Scrub Typhus: Fighting Two Fronts

Scrub typhus and leptospirosis may have overlapping febrile syndromes and develop to cause multiorgan dysfunction, and the coinfection can also be dangerous.In both diseases, pulmonary involvement takes place, but diffuse alveolar hemorrhage (DAH) is rare and has a high mortality rate.We describe a 59-year-old farmer presenting with high-grade fever, dyspnea, and a dry cough, who had developed hemoptysis and acute kidney injury.Laboratory analysis revealed anemia, leukocytosis, thrombocytopenia, hyperbilirubinemia, and renal insufficiency.Immunoglobulin M (IgM) testing positive for scrub typhus and leptospirosis was confirmed by serology.The chest images demonstrated diffuse infiltrates of the alveoli, which were characteristic of DAH.Supportive care, broad-spectrum antibiotics, and doxycycline led to slow recovery and discharge.The case shows that dual infections in an endemic setting should be considered and DAH recognized at early stages.Supportive measures and early serological testing can improve the outcomes with doxycycline.

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Publication Details

Journal
Bengal Physician Journal
Published
2026-09-29
DOI
https://doi.org/10.5005/jp-journals-10070-8138
Primary Topic
Vector-borne infectious diseases
Type
article
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article

Alveolar Hemorrhage in Weil\'s Disease and Coexisting Scrub Typhus: Fighting Two Fronts

Kaushik Ghosh, Soumodip Saha, Saikat Sadhukhan, Sonali Ghosh
Bengal Physician Journal
Vector-borne infectious diseases
article

Alveolar Hemorrhage in Weil\'s Disease and Coexisting Scrub Typhus: Fighting Two Fronts

Kaushik Ghosh, Soumodip Saha, Saikat Sadhukhan, Sonali Ghosh
article en

Abstract

Scrub typhus and leptospirosis may have overlapping febrile syndromes and develop to cause multiorgan dysfunction, and the coinfection can also be dangerous.In both diseases, pulmonary involvement takes place, but diffuse alveolar hemorrhage (DAH) is rare and has a high mortality rate.We describe a 59-year-old farmer presenting with high-grade fever, dyspnea, and a dry cough, who had developed hemoptysis and acute kidney injury.Laboratory analysis revealed anemia, leukocytosis, thrombocytopenia, hyperbilirubinemia, and renal insufficiency.Immunoglobulin M (IgM) testing positive for scrub typhus and leptospirosis was confirmed by serology.The chest images demonstrated diffuse infiltrates of the alveoli, which were characteristic of DAH.Supportive care, broad-spectrum antibiotics, and doxycycline led to slow recovery and discharge.The case shows that dual infections in an endemic setting should be considered and DAH recognized at early stages.Supportive measures and early serological testing can improve the outcomes with doxycycline.

Bengal Physician JournalVol. 13(3)
Institute of Post Graduate Medical Education and Research (IN), Murshidabad Medical College and Hospital (IN)
Good health and well-being
Openalex Percentile: Top 10%
Vector-borne infectious diseases
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