Personalized drug discovery from rare diseases to cancer

Precision medicine selects individual treatments from a small toolbox of therapies already available. Personalized drug discovery (PDD) brings this concept one step ahead, developing drugs for individual patient’s diseases. Currently, PDD is being developed for rare disorders, where conventional drug discovery paradigms are non-applicable due to small patient sizes, but also for cancer. As a new frontier in precision medicine, PDD should be upscaled in rare and non-rare diseases.

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Publication Details

Journal
npj Drug Discovery.
Published
2026-09-30
DOI
https://doi.org/10.1038/s44386-026-00085-y
Primary Topic
Genomics and Rare Diseases
Type
article
Field-Weighted Citation Impact
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article

Personalized drug discovery from rare diseases to cancer

Vladimir L. Katanaev
npj Drug Discovery.
Genomics and Rare Diseases
article

Personalized drug discovery from rare diseases to cancer

Vladimir L. Katanaev
article en

Abstract

Precision medicine selects individual treatments from a small toolbox of therapies already available. Personalized drug discovery (PDD) brings this concept one step ahead, developing drugs for individual patient’s diseases. Currently, PDD is being developed for rare disorders, where conventional drug discovery paradigms are non-applicable due to small patient sizes, but also for cancer. As a new frontier in precision medicine, PDD should be upscaled in rare and non-rare diseases.

npj Drug Discovery.Vol. 3(1)
University of Geneva (CH), Hamad bin Khalifa University (QA)
Openalex Percentile: Top 12%
Genomics and Rare Diseases
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