Pure Neuritic Leprosy Masquerading as Diabetic Neuropathy: A Diagnostic Challenge

Diabetes mellitus is a well-recognized cause of peripheral neuropathy, often presenting with numbness, paresthesia, and distal limb weakness.However, this common attribution can obscure the diagnosis of more insidious conditions, especially in regions where diseases like leprosy are endemic.Here, we report the case of a 50-year-old woman with longstanding, poorly controlled diabetes mellitus who presented with chronic numbness, distal limb weakness, and a non-healing digital ulcer.Initially suspected to have diabetic neuropathy, further clinical evaluation and histopathological confirmation revealed a diagnosis of pure neuritic type leprosy, a rare and often overlooked form of Hansen's disease.This case emphasizes the necessity of considering alternative diagnoses, including infectious etiologies, when neuropathic symptoms persist despite standard management, particularly in endemic regions.Early identification and appropriate intervention can significantly alter the disease trajectory, prevent irreversible nerve damage, and improve the quality of life.

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Publication Details

Journal
Bengal Physician Journal
Published
2026-09-29
DOI
https://doi.org/10.5005/jp-journals-10070-8168
Primary Topic
Leprosy Research and Treatment
Type
article
Field-Weighted Citation Impact
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article

Pure Neuritic Leprosy Masquerading as Diabetic Neuropathy: A Diagnostic Challenge

Kaushik Basu, Alivia Nandi, Soumya Swaraj Mondal, Asaf A Mondal et al.
Bengal Physician Journal
Leprosy Research and Treatment
article

Pure Neuritic Leprosy Masquerading as Diabetic Neuropathy: A Diagnostic Challenge

Kaushik Basu, Alivia Nandi, Soumya Swaraj Mondal, Asaf A Mondal, Kaustav Borthakur
article en

Abstract

Diabetes mellitus is a well-recognized cause of peripheral neuropathy, often presenting with numbness, paresthesia, and distal limb weakness.However, this common attribution can obscure the diagnosis of more insidious conditions, especially in regions where diseases like leprosy are endemic.Here, we report the case of a 50-year-old woman with longstanding, poorly controlled diabetes mellitus who presented with chronic numbness, distal limb weakness, and a non-healing digital ulcer.Initially suspected to have diabetic neuropathy, further clinical evaluation and histopathological confirmation revealed a diagnosis of pure neuritic type leprosy, a rare and often overlooked form of Hansen's disease.This case emphasizes the necessity of considering alternative diagnoses, including infectious etiologies, when neuropathic symptoms persist despite standard management, particularly in endemic regions.Early identification and appropriate intervention can significantly alter the disease trajectory, prevent irreversible nerve damage, and improve the quality of life.

Bengal Physician JournalVol. 13(3)
Medical College and Hospital, Kolkata (IN)
Openalex Percentile: Top 12%
Leprosy Research and Treatment
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