Hiccups to hyponatremic encephalopathy: A rare presentation of acute water intoxication in a patient after uroflowmetry

ABSTRACT Benign prostatic hyperplasia (BPH) commonly presents with lower urinary tract symptoms and requires preprocedural bladder filling for urologic evaluation. A 61-year-old male with BPH, diabetes, and hypertension developed altered sensorium, behavioral changes, hiccups, and a single episode of generalized tonic–clonic seizure after consuming 4 L of water during 2 h prior to uroflowmetry and ultrasound. Investigations showed hypotonic hyponatremia (serum sodium: 109 mEq/L). Other causes were excluded, and prompt treatment with hypertonic saline and fluid restriction was initiated, resulting in full recovery. Acute water intoxication causing dilutional hyponatremia is a rare but preventable complication requiring awareness and proper hydration guidance, especially in the elderly.

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Publication Details

Journal
Indian Journal of Urology
Published
2026-09-29
DOI
https://doi.org/10.4103/iju.iju_216_26
Primary Topic
Pathogenesis and Treatment of Hiccups
Type
article
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article

Hiccups to hyponatremic encephalopathy: A rare presentation of acute water intoxication in a patient after uroflowmetry

Zainab Mehdi, Amit Mishra, Hanny C Japhina
Indian Journal of Urology
Pathogenesis and Treatment of Hiccups
article

Hiccups to hyponatremic encephalopathy: A rare presentation of acute water intoxication in a patient after uroflowmetry

Zainab Mehdi, Amit Mishra, Hanny C Japhina
article en

Abstract

ABSTRACT Benign prostatic hyperplasia (BPH) commonly presents with lower urinary tract symptoms and requires preprocedural bladder filling for urologic evaluation. A 61-year-old male with BPH, diabetes, and hypertension developed altered sensorium, behavioral changes, hiccups, and a single episode of generalized tonic–clonic seizure after consuming 4 L of water during 2 h prior to uroflowmetry and ultrasound. Investigations showed hypotonic hyponatremia (serum sodium: 109 mEq/L). Other causes were excluded, and prompt treatment with hypertonic saline and fluid restriction was initiated, resulting in full recovery. Acute water intoxication causing dilutional hyponatremia is a rare but preventable complication requiring awareness and proper hydration guidance, especially in the elderly.

Indian Journal of UrologyVol. 42(4)
All India Institute of Medical Sciences (IN)
Clean water and sanitation
Openalex Percentile: Top 12%
Pathogenesis and Treatment of Hiccups
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Hiccups to hyponatremic encephalopathy: A rare presentation of acute water intoxication in a patient after uroflowmetry — Zainab Mehdi, Amit Mishra, et al. · Indian Journal of Urology (2026) | TGRS Research Map | TGRS