The wound edge exists in the photograph: rule-based, auditable measurement against a physical standard in a porcine model (with full Portuguese manuscript, code, data and audit trail)

▶ RUN IT YOURSELF / RODE VOCÊ MESMO — live demo in your browser / demonstração ao vivo no navegador (PT/EN): https://fabiohumaniza-cyber.github.io/deolhonapele/ Manuscript (Portuguese, with English title, abstract and Box 1), frozen rule-based engine (SOLIZ v0), output data, supplements S1–S9, public demo (JavaScript port validated digit-for-digit against the frozen engine) and complete audit trail — pre-registrations, hashes and a dated error log ("the error notebook is part of the method"). Headline: on 12 held-out day-3 porcine punch wounds, against blind expert-level tracing, the frozen engine scored paired Dice (means) 0.967 vs 0.926 for a 20-mm circle centered on the tracing (95% CI +0.020 to +0.064; Wilcoxon p = 0.002); a circle that never looks at the photograph nearly ties expert tracing — so we propose every edge-agreement table report this geometric null, paired, same statistic on both sides. Run without being told the diameter, the engine measured 300.3 mm² (day 1, n = 36) against the 314.2 mm² nominal punch. No training; no new animals; public data only (Dryad doi:10.5061/dryad.0rxwdbsbr; Zlobina et al. 2025, Sci Data 12:1635; area curve from Yang et al. 2026, JID Innovations 6(3):100458). A cross-species replication on the same group's public mouse dataset (doi:10.25338/B84W8Q) is pre-registered with hashes anterior to this DOI; no image of that dataset was opened before deposit. Method under patent application BR 10 2026 024571 2 (INPI, 2026-09-29) and software registration BR 51 2026 008413-0; see LICENSE.txt (texts/data CC BY 4.0; code source-available, research-free, commercial use licensed).

Authors

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-09-30
DOI
https://doi.org/10.5281/zenodo.23062848
Primary Topic
Wound Healing and Treatments
Type
preprint
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The wound edge exists in the photograph: rule-based, auditable measurement against a physical standard in a porcine model (with full Portuguese manuscript, code, data and audit trail)

Fabio da Camara Oliveira Ferreira
Zenodo (CERN European Organization for Nuclear Research)
Wound Healing and Treatments
preprint

The wound edge exists in the photograph: rule-based, auditable measurement against a physical standard in a porcine model (with full Portuguese manuscript, code, data and audit trail)

Fabio da Camara Oliveira Ferreira
preprint en

Abstract

▶ RUN IT YOURSELF / RODE VOCÊ MESMO — live demo in your browser / demonstração ao vivo no navegador (PT/EN): https://fabiohumaniza-cyber.github.io/deolhonapele/ Manuscript (Portuguese, with English title, abstract and Box 1), frozen rule-based engine (SOLIZ v0), output data, supplements S1–S9, public demo (JavaScript port validated digit-for-digit against the frozen engine) and complete audit trail — pre-registrations, hashes and a dated error log ("the error notebook is part of the method"). Headline: on 12 held-out day-3 porcine punch wounds, against blind expert-level tracing, the frozen engine scored paired Dice (means) 0.967 vs 0.926 for a 20-mm circle centered on the tracing (95% CI +0.020 to +0.064; Wilcoxon p = 0.002); a circle that never looks at the photograph nearly ties expert tracing — so we propose every edge-agreement table report this geometric null, paired, same statistic on both sides. Run without being told the diameter, the engine measured 300.3 mm² (day 1, n = 36) against the 314.2 mm² nominal punch. No training; no new animals; public data only (Dryad doi:10.5061/dryad.0rxwdbsbr; Zlobina et al. 2025, Sci Data 12:1635; area curve from Yang et al. 2026, JID Innovations 6(3):100458). A cross-species replication on the same group's public mouse dataset (doi:10.25338/B84W8Q) is pre-registered with hashes anterior to this DOI; no image of that dataset was opened before deposit. Method under patent application BR 10 2026 024571 2 (INPI, 2026-09-29) and software registration BR 51 2026 008413-0; see LICENSE.txt (texts/data CC BY 4.0; code source-available, research-free, commercial use licensed).

Zenodo (CERN European Organization for Nuclear Research)
Wound Healing and Treatments
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The wound edge exists in the photograph: rule-based, auditable measurement against a physical standard in a porcine model (with full Portuguese manuscript, code, data and audit trail) — Fabio da Camara Oliveira Ferreira · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS