SYNTHESIS AND HIRSCHFELD SURFACE ANALYSIS OF ORGANIC SALT CRYSTAL OF LEVOFLOXACIN FORMED WITH DITHIONATE ANION

Background. The creation of safe and highly effective drugs in pharmacology is relevant.Purpose. Synthesis of molecular complexes of organic salts based on levofloxacin, determination ofthe structure and crystallographic size.Methodology. The crystal structures of the complex (X Calibur-R Oxford Diffraction) were registered with the corresponding programs, the Hirschfeld surface analysis of the synthesized complex was performed.Originality. The surface analysis of the complex according to Hirschfeld was carried out and the energies of intermolecular interactions were calculated.Findings. A new molecular complex of the salt [LEVH]2∙[S2O6]∙2H2O was obtained. Its molecularcharacteristics and crystal structure were determined by X-ray structural analysis.Key words: levofloxacin, organic salt, dithionate anion, Hirschfeld surface, intermolecular interaction energy.Highlights:- a complex compound consisting of three components;- a molecular complex compound in the form of an organic salt;- it belongs to hydrated complexes of ionic nature