Multiple Primary Malignancies Involving Papillary Thyroid Carcinoma: A Three‐Case Series

ABSTRACT Papillary thyroid carcinoma (PTC) may be associated with second primary malignancies. We report three cases with melanoma, diffuse large B‐cell lymphoma, and breast carcinoma occurring synchronously or metachronously. All cases highlighted diagnostic challenges in distinguishing metastasis from new primaries, emphasizing the necessity of histopathologic confirmation and multidisciplinary management.

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Publication Details

Journal
Clinical Case Reports
Published
2026-09-29
DOI
https://doi.org/10.1002/ccr3.73594
Primary Topic
Multiple and Secondary Primary Cancers
Type
article
Field-Weighted Citation Impact
0.00
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article

Multiple Primary Malignancies Involving Papillary Thyroid Carcinoma: A Three‐Case Series

Katayoon Ghasemi, Amirhossein Rezaei Latifi, Mohammad Salari
Clinical Case Reports
Multiple and Secondary Primary Cancers
article

Multiple Primary Malignancies Involving Papillary Thyroid Carcinoma: A Three‐Case Series

Katayoon Ghasemi, Amirhossein Rezaei Latifi, Mohammad Salari
article en

Abstract

ABSTRACT Papillary thyroid carcinoma (PTC) may be associated with second primary malignancies. We report three cases with melanoma, diffuse large B‐cell lymphoma, and breast carcinoma occurring synchronously or metachronously. All cases highlighted diagnostic challenges in distinguishing metastasis from new primaries, emphasizing the necessity of histopathologic confirmation and multidisciplinary management.

Clinical Case ReportsVol. 14(10)
Hormozgan University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 11%
Multiple and Secondary Primary Cancers
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