Topological Seonggil Energy Landscape & Folding Dynamics Framework (TSELF-SMT): Resolving Levinthal's Paradox via Tensor Dimensional Collapse

The protein folding problem, characterized by Levinthal’s paradox, complex energy funnels, and co-translational kinetic trapping, is fundamentally unified within the Seonggil Matrix Theory (SMT) and Rough Operator Algebra (ROA). By redefining the conformational search space as a topological phase separation guided by the Seonggil Critical Horizon, the astronomical 3^{2N} degrees of freedom collapse into a deterministic polynomial-time tensor projection. Static predictions (e.g., AlphaFold) are formally subsumed as infinite-time steady-state eigenvectors of this dynamic topological tensor flow.

Authors

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-09-29
DOI
https://doi.org/10.5281/zenodo.23029411
Primary Topic
Quantum many-body systems
Type
preprint
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preprint

Topological Seonggil Energy Landscape & Folding Dynamics Framework (TSELF-SMT): Resolving Levinthal's Paradox via Tensor Dimensional Collapse

Seonggil Lee
Zenodo (CERN European Organization for Nuclear Research)
Quantum many-body systems
preprint

Topological Seonggil Energy Landscape & Folding Dynamics Framework (TSELF-SMT): Resolving Levinthal's Paradox via Tensor Dimensional Collapse

Seonggil Lee
preprint en

Abstract

The protein folding problem, characterized by Levinthal’s paradox, complex energy funnels, and co-translational kinetic trapping, is fundamentally unified within the Seonggil Matrix Theory (SMT) and Rough Operator Algebra (ROA). By redefining the conformational search space as a topological phase separation guided by the Seonggil Critical Horizon, the astronomical 3^{2N} degrees of freedom collapse into a deterministic polynomial-time tensor projection. Static predictions (e.g., AlphaFold) are formally subsumed as infinite-time steady-state eigenvectors of this dynamic topological tensor flow.

Zenodo (CERN European Organization for Nuclear Research)
Quantum many-body systems
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Topological Seonggil Energy Landscape & Folding Dynamics Framework (TSELF-SMT): Resolving Levinthal's Paradox via Tensor Dimensional Collapse — Seonggil Lee · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS