Levofloxacin-induced Ataxia in a Child After Complicated Pneumonia

A 6-year-old child with complicated necrotizing pneumonia developed acute ataxia, urticarial rash and urinary incontinence on the third day of levofloxacin therapy. No structural abnormalities were found on imaging. The antibiotic was discontinued, and corticosteroids with antihistamines were initiated, leading to complete symptom resolution without sequelae. This pediatric case underscores the need for vigilance regarding levofloxacin-induced movement disorders, even with short-term use.

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Publication Details

Journal
The Pediatric Infectious Disease Journal
Published
2026-09-29
DOI
https://doi.org/10.1097/inf.0000000000005422
Primary Topic
Antibiotics Pharmacokinetics and Efficacy
Type
article
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article

Levofloxacin-induced Ataxia in a Child After Complicated Pneumonia

Cláudio D’Elia, Giovanna D’Elia Ganem, Maria Kokkinovrachos de Azevedo
The Pediatric Infectious Disease Journal
Antibiotics Pharmacokinetics and Efficacy
article

Levofloxacin-induced Ataxia in a Child After Complicated Pneumonia

Cláudio D’Elia, Giovanna D’Elia Ganem, Maria Kokkinovrachos de Azevedo
article en

Abstract

A 6-year-old child with complicated necrotizing pneumonia developed acute ataxia, urticarial rash and urinary incontinence on the third day of levofloxacin therapy. No structural abnormalities were found on imaging. The antibiotic was discontinued, and corticosteroids with antihistamines were initiated, leading to complete symptom resolution without sequelae. This pediatric case underscores the need for vigilance regarding levofloxacin-induced movement disorders, even with short-term use.

The Pediatric Infectious Disease Journal
Universidade Estadual de Ciências da Saúde de Alagoas (BR), Hospital Central da Polícia Militar (BR)
Good health and well-being
Openalex Percentile: Top 13%
Antibiotics Pharmacokinetics and Efficacy
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