Early-Onset Multiple Necrobiosis Lipoidica in a Child with Type 1 Diabetes Mellitus

Necrobiosis lipoidica is uncommon in childhood, and a multifocal presentation early in the course of type 1 diabetes mellitus appears to be infrequently reported. In our patient, multiple lesions developed within 3 years of diabetes diagnosis, despite the absence of overt microvascular complications. The persistence of lesions alongside recurrent episodes of ketoacidosis may suggest a potential association between suboptimal metabolic control and cutaneous microangiopathic changes; however, causality cannot be established on the basis of a single case. Early recognition of such lesions may be clinically relevant, as they may prompt careful metabolic evaluation and closer follow-up in affected children.

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Journal
Journal of Clinical Research in Pediatric Endocrinology
Published
2026-09-28
DOI
https://doi.org/10.4274/jcrpe.galenos.2026.2026-1-1
Primary Topic
Skin Diseases and Diabetes
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article
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article

Early-Onset Multiple Necrobiosis Lipoidica in a Child with Type 1 Diabetes Mellitus

Emel Gül Açıkgöz, Gökhan Şahin, Ozge Yanik, Şeyma Koca et al.
Journal of Clinical Research in Pediatric Endocrinology
Skin Diseases and Diabetes
article

Early-Onset Multiple Necrobiosis Lipoidica in a Child with Type 1 Diabetes Mellitus

Emel Gül Açıkgöz, Gökhan Şahin, Ozge Yanik, Şeyma Koca, Tuğba Kontbay Çetin
article en

Abstract

Necrobiosis lipoidica is uncommon in childhood, and a multifocal presentation early in the course of type 1 diabetes mellitus appears to be infrequently reported. In our patient, multiple lesions developed within 3 years of diabetes diagnosis, despite the absence of overt microvascular complications. The persistence of lesions alongside recurrent episodes of ketoacidosis may suggest a potential association between suboptimal metabolic control and cutaneous microangiopathic changes; however, causality cannot be established on the basis of a single case. Early recognition of such lesions may be clinically relevant, as they may prompt careful metabolic evaluation and closer follow-up in affected children.

Journal of Clinical Research in Pediatric Endocrinology
Ondokuz Mayıs University (TR), Samsun University (TR), Sağlık Bilimleri Üniversitesi (TR)
Good health and well-being
Openalex Percentile: Top 9%
Skin Diseases and Diabetes
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Early-Onset Multiple Necrobiosis Lipoidica in a Child with Type 1 Diabetes Mellitus — Emel Gül Açıkgöz, Gökhan Şahin, et al. · Journal of Clinical Research in Pediatric Endocrinology (2026) | TGRS Research Map | TGRS