Molecular Mechanisms of Resistance to KRAS G12C Inhibitors in NSCLC- From Genomic Evolution to TME Adaptation

targeted therapies and discuss evolving therapeutic strategies designed to overcome adaptive resistance in KRAS mutant malignancies.

Authors

Publication Details

Journal
Journal of drug targeting
Published
2026-09-28
DOI
https://doi.org/10.1080/1061186x.2026.2741202
Primary Topic
Protein Kinase Regulation and GTPase Signaling
Type
article
Field-Weighted Citation Impact
0.00
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article

Molecular Mechanisms of Resistance to KRAS G12C Inhibitors in NSCLC- From Genomic Evolution to TME Adaptation

Mercy Jacquiline, Simmy Mehta, Neeru Singh, Yugshree Vidhyarthi
Journal of drug targeting
Protein Kinase Regulation and GTPase Signaling
article

Molecular Mechanisms of Resistance to KRAS G12C Inhibitors in NSCLC- From Genomic Evolution to TME Adaptation

Mercy Jacquiline, Simmy Mehta, Neeru Singh, Yugshree Vidhyarthi
article en

Abstract

targeted therapies and discuss evolving therapeutic strategies designed to overcome adaptive resistance in KRAS mutant malignancies.

Journal of drug targeting
Zero hunger
Openalex Percentile: Top 19%
Protein Kinase Regulation and GTPase Signaling
DOISourceOpenAlex
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Molecular Mechanisms of Resistance to KRAS G12C Inhibitors in NSCLC- From Genomic Evolution to TME Adaptation — Mercy Jacquiline, Simmy Mehta, et al. · Journal of drug targeting (2026) | TGRS Research Map | TGRS