Study of a Frugal Design Picosecond Laser System for Laser‐Assisted Corneal Surgery

ABSTRACT Femtosecond lasers have long been the gold standard for corneal laser‐assisted surgery, but their high cost limits widespread use. This study challenges their supremacy by investigating a cost‐effective alternative: a frugal all‐fiber picosecond laser source. We first conduct a pump‐probe experiment to characterize cavitation bubbles in water based on the laser pulse's temporal profile. Picosecond pulses concentrate energy in a confined volume near the focal point, allowing for more precise material interaction than femtosecond pulses. A distortion in the temporal profile, often seen as a flaw, paradoxically further reduces cavitation bubble size. These findings are then applied to ex vivo porcine cornea cutting tests. Results show that 1.5 ps pulses with a distorted profile create sharp, consistent cuts. This study reveals that a cost‐effective picosecond laser can rival femtosecond lasers in precision, paving the way for more accessible corneal laser‐assisted surgery.

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Publication Details

Journal
Journal of Biophotonics
Published
2026-09-28
DOI
https://doi.org/10.1002/jbio.70356
Primary Topic
Corneal surgery and disorders
Type
article
Field-Weighted Citation Impact
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article

Study of a Frugal Design Picosecond Laser System for Laser‐Assisted Corneal Surgery

David Touboul, Valentine Saunier, Théo Guilberteau, Anaïs Langlois et al.
Journal of Biophotonics
Corneal surgery and disorders
article

Study of a Frugal Design Picosecond Laser System for Laser‐Assisted Corneal Surgery

David Touboul, Valentine Saunier, Théo Guilberteau, Anaïs Langlois, Pierre Balage, Florent Deloison, John A. P. Lopez, Inka Manek-Hönninger, Maxime Quirke, Thomas Hemery
article en

Abstract

ABSTRACT Femtosecond lasers have long been the gold standard for corneal laser‐assisted surgery, but their high cost limits widespread use. This study challenges their supremacy by investigating a cost‐effective alternative: a frugal all‐fiber picosecond laser source. We first conduct a pump‐probe experiment to characterize cavitation bubbles in water based on the laser pulse's temporal profile. Picosecond pulses concentrate energy in a confined volume near the focal point, allowing for more precise material interaction than femtosecond pulses. A distortion in the temporal profile, often seen as a flaw, paradoxically further reduces cavitation bubble size. These findings are then applied to ex vivo porcine cornea cutting tests. Results show that 1.5 ps pulses with a distorted profile create sharp, consistent cuts. This study reveals that a cost‐effective picosecond laser can rival femtosecond lasers in precision, paving the way for more accessible corneal laser‐assisted surgery.

Journal of BiophotonicsVol. 19(10)
Centre National de la Recherche Scientifique (FR), Université de Bordeaux (FR), Université Paris-Est Créteil (FR), Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR), Centre Hospitalier Universitaire de Bordeaux (FR), Centre Lasers Intenses et Applications (FR), ALPhANOV (France) (FR), Centre Hospitalier Universitaire de Rouen (FR), Double Helix (United States) (US), Helix (United States) (US)
Openalex Percentile: Top 12%
Corneal surgery and disorders
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Study of a Frugal Design Picosecond Laser System for Laser‐Assisted Corneal Surgery — David Touboul, Valentine Saunier, et al. · Journal of Biophotonics (2026) | TGRS Research Map | TGRS