Broadband wearable acoustic sensing for continuous cardiopulmonary monitoring

Abstract The human body continuously generates weak, broadband acoustic–mechanical signals that encode rich cardiopulmonary information, yet their reliable capture in real-world settings remains constrained by motion artifacts, limited bandwidth, and suboptimal mechanical coupling. Here, we present a wearable, wireless stethoscope that enables high-fidelity acquisition of heart and respiratory sounds through a mechanically compliant, broadband sensing interface. The system is built on a piezoelectric micromachined ultrasonic transducer (PMUT) engineered to achieve ultrahigh sensitivity (–167.5 dB), a wide operating bandwidth (10 Hz–10 kHz), and a flat frequency response (±0.5 dB), enabling accurate reconstruction of subtle physiological signals across a broad spectral range. Integration with soft, skin-conformal packaging and a robust wireless readout minimizes motion-induced noise and supports stable, long-term monitoring during daily activities. Validation across multiple participants demonstrates strong agreement with clinical-grade systems, including consistent auscultation at standard cardiac sites and accurate heart-rate tracking during dynamic exercise. Furthermore, coupling the sensing platform with a residual neural network enables automated classification of five respiratory states (awake, asleep, apnea, rhonchi, and wheeze) with an accuracy of 98.7%. This work establishes a scalable, low-cost framework for continuous, high-fidelity cardiopulmonary monitoring in real-world environments.

Authors

Publication Details

Journal
Microsystems & Nanoengineering
Published
2026-09-29
DOI
https://doi.org/10.1038/s41378-026-01460-5
Primary Topic
Phonocardiography and Auscultation Techniques
Type
article
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Broadband wearable acoustic sensing for continuous cardiopulmonary monitoring

Xiaojing Mu, Pengfan Wu, Hanjie Dou, Jiaqian Yang et al.
Microsystems & Nanoengineering
Phonocardiography and Auscultation Techniques
article

Broadband wearable acoustic sensing for continuous cardiopulmonary monitoring

Xiaojing Mu, Pengfan Wu, Hanjie Dou, Jiaqian Yang, Dongxiao Li, Tao Liu, Hengyu Guo, Hongliang Wang
article en

Abstract

Abstract The human body continuously generates weak, broadband acoustic–mechanical signals that encode rich cardiopulmonary information, yet their reliable capture in real-world settings remains constrained by motion artifacts, limited bandwidth, and suboptimal mechanical coupling. Here, we present a wearable, wireless stethoscope that enables high-fidelity acquisition of heart and respiratory sounds through a mechanically compliant, broadband sensing interface. The system is built on a piezoelectric micromachined ultrasonic transducer (PMUT) engineered to achieve ultrahigh sensitivity (–167.5 dB), a wide operating bandwidth (10 Hz–10 kHz), and a flat frequency response (±0.5 dB), enabling accurate reconstruction of subtle physiological signals across a broad spectral range. Integration with soft, skin-conformal packaging and a robust wireless readout minimizes motion-induced noise and supports stable, long-term monitoring during daily activities. Validation across multiple participants demonstrates strong agreement with clinical-grade systems, including consistent auscultation at standard cardiac sites and accurate heart-rate tracking during dynamic exercise. Furthermore, coupling the sensing platform with a residual neural network enables automated classification of five respiratory states (awake, asleep, apnea, rhonchi, and wheeze) with an accuracy of 98.7%. This work establishes a scalable, low-cost framework for continuous, high-fidelity cardiopulmonary monitoring in real-world environments.

Microsystems & NanoengineeringVol. 12(1)
Openalex Percentile: Top 12%
Phonocardiography and Auscultation Techniques
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Broadband wearable acoustic sensing for continuous cardiopulmonary monitoring — Xiaojing Mu, Pengfan Wu, et al. · Microsystems & Nanoengineering (2026) | TGRS Research Map | TGRS