Treat-to-target strategies for low-density lipoprotein cholesterol and triglyceride levels for primary and secondary prevention of cardiovascular disease in adults with dyslipidaemia

OBJECTIVES: This is a protocol for a Cochrane review (intervention). The objectives are as follows: To evaluate the benefits and harms of a treat-to-target (goal-directed) strategy versus a no-target strategy for lipid-lowering therapy in the primary and secondary prevention of cardiovascular disease in adults with dyslipidaemia.

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Journal
Cochrane Database of Systematic Reviews
Published
2026-09-28
DOI
https://doi.org/10.1002/14651858.cd016388
Primary Topic
Lipoproteins and Cardiovascular Health
Type
article
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article

Treat-to-target strategies for low-density lipoprotein cholesterol and triglyceride levels for primary and secondary prevention of cardiovascular disease in adults with dyslipidaemia

Juan Víctor Ariel Franco, Camila Micaela Escobar Liquitay, Kamyar Shokraee, Nicole Skoetz et al.
Cochrane Database of Systematic Reviews
Lipoproteins and Cardiovascular Health
article

Treat-to-target strategies for low-density lipoprotein cholesterol and triglyceride levels for primary and secondary prevention of cardiovascular disease in adults with dyslipidaemia

Juan Víctor Ariel Franco, Camila Micaela Escobar Liquitay, Kamyar Shokraee, Nicole Skoetz, Ana-Mihaela Zorger, Petek Eylul Taneri, Siavosh Olfati, Brenda Bongaerts
article en

Abstract

OBJECTIVES: This is a protocol for a Cochrane review (intervention). The objectives are as follows: To evaluate the benefits and harms of a treat-to-target (goal-directed) strategy versus a no-target strategy for lipid-lowering therapy in the primary and secondary prevention of cardiovascular disease in adults with dyslipidaemia.

Cochrane Database of Systematic ReviewsVol. 2026(9)
University of Cologne (DE), Hospital Italiano de Buenos Aires (AR), University Hospital Cologne (DE), Universidad Hospital Italiano (AR), Heinrich Heine University Düsseldorf (DE), Cochrane (GB)
Good health and well-being
Openalex Percentile: Top 9%
Lipoproteins and Cardiovascular Health
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Treat-to-target strategies for low-density lipoprotein cholesterol and triglyceride levels for primary and secondary prevention of cardiovascular disease in adults with dyslipidaemia — Juan Víctor Ariel Franco, Camila Micaela Escobar Liquitay, et al. · Cochrane Database of Systematic Reviews (2026) | TGRS Research Map | TGRS