Outside Front Cover: Adaptive Hydrogenation of Alkynes Using CO as a Molecular Trigger to Selectively Produce Alkanes or Z ‐Alkenes

One Catalyst, Two Reactivities: CO makes the Switch and Enables Adaptivity. Supported palladium nanoparticles adapt to their environment to hydrogenate alkynes to alkanes under H2, and to Z-alkenes upon incorporation of CO. The CO-triggered selectivity switch is fully reversible, rapid, and robust, and enables adaptive hydrogenation of 37 structurally diverse alkynes to valuable bioactive and pharmaceutical intermediates. In the Research Article e9302519, Walter Leitner, Alexis Bordet, and co-workers. Artwork by Dr. Johannes Zenner.

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Publication Details

Journal
Angewandte Chemie International Edition
Published
2026-09-28
DOI
https://doi.org/10.1002/anie.2026-m2509041400
Primary Topic
Asymmetric Hydrogenation and Catalysis
Type
article
Field-Weighted Citation Impact
0.00
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Outside Front Cover: Adaptive Hydrogenation of Alkynes Using CO as a Molecular Trigger to Selectively Produce Alkanes or Z ‐Alkenes

Lachlan Sharp‐Bucknall, Manisha Durai, Walid Hetaba, Walter Leitner et al.
Angewandte Chemie International Edition
Asymmetric Hydrogenation and Catalysis
article

Outside Front Cover: Adaptive Hydrogenation of Alkynes Using CO as a Molecular Trigger to Selectively Produce Alkanes or Z ‐Alkenes

Lachlan Sharp‐Bucknall, Manisha Durai, Walid Hetaba, Walter Leitner, Jacob Johny, Alexis Bordet, Tim Alexander Schubert, John‐Tommes Krzeslack
article en

Abstract

One Catalyst, Two Reactivities: CO makes the Switch and Enables Adaptivity. Supported palladium nanoparticles adapt to their environment to hydrogenate alkynes to alkanes under H2, and to Z-alkenes upon incorporation of CO. The CO-triggered selectivity switch is fully reversible, rapid, and robust, and enables adaptive hydrogenation of 37 structurally diverse alkynes to valuable bioactive and pharmaceutical intermediates. In the Research Article e9302519, Walter Leitner, Alexis Bordet, and co-workers. Artwork by Dr. Johannes Zenner.

Angewandte Chemie International Edition
Max Planck Institute for Chemical Energy Conversion (DE), RWTH Aachen University (DE)
Openalex Percentile: Top 27%
Asymmetric Hydrogenation and Catalysis
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