Amyloid A amyloidosis of kidney and minor labial salivary gland result from right knee infection by Methicillin-resistant Staphylococcus epidermidis

Amyloidosis is a group of diseases caused by the deposition of abnormal protein fibrils in the extracellular space. These amyloid deposits can affect almost any organ system, with the kidney being the most commonly involved organ. In the present case, systemic amyloid A deposits caused by a periprosthetic joint infection following knee arthroplasty were identified in both the kidney and the salivary gland, the latter being rarely reported in amyloid A (AA) amyloidosis. The case was successfully treated, owing to timely identification of the underlying causes of proteinuria and xerostomia symptom, along with the prompt initiation of appropriate antimicrobial therapy and surgical intervention.