Left Atrial Appendage Occlusion—Is the Case Now Closed?

This Viewpoint disucsses how the results of CLOSURE-AF and CHAMPION-AF should inform decision-making regarding treatment with direct oral anticoagulants vs left atrial appendage closure for left atrial appendage occlusion.

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Publication Details

Journal
JAMA Neurology
Published
2026-09-28
DOI
https://doi.org/10.1001/jamaneurol.2026.3292
Primary Topic
Atrial Fibrillation Management and Outcomes
Type
article
Field-Weighted Citation Impact
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article

Left Atrial Appendage Occlusion—Is the Case Now Closed?

Rod S. Passman, David Seiffge, Charlotte Cordonnier, Richard A. Bernstein
JAMA Neurology
Atrial Fibrillation Management and Outcomes
article

Left Atrial Appendage Occlusion—Is the Case Now Closed?

Rod S. Passman, David Seiffge, Charlotte Cordonnier, Richard A. Bernstein
article en

Abstract

This Viewpoint disucsses how the results of CLOSURE-AF and CHAMPION-AF should inform decision-making regarding treatment with direct oral anticoagulants vs left atrial appendage closure for left atrial appendage occlusion.

JAMA Neurology
Northwestern University (US), University of Bern (CH), Inserm (FR), Université de Lille (FR), University Hospital of Bern (CH), Centre Hospitalier Universitaire de Lille (FR)
Peace, Justice and strong institutions
Openalex Percentile: Top 11%
Atrial Fibrillation Management and Outcomes
DOISourceOpenAlex
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