MICROPAPULAR CUTANEOUS SARCOIDOSIS: CLINICODERMOSCOPIC AND HISTOPATHOLOGICAL CORRELATION

Sarcoidosis is a multisystem inflammatory disease characterized by noncaseating granulomas, with cutaneous involvement presenting in various morphological patterns. Micropapular cutaneous sarcoidosis is a rare clinical variant that may pose a diagnostic challenge. We report a 64-year-old woman presenting with numerous yellowish-pink millimetric papules on the posterior trunk. Dermoscopy revealed multiple yellow-orange structureless areas on a pink background, while histopathological examination demonstrated non-necrotizing “naked” granulomas with multinucleated giant cells. Systemic evaluation revealed lymphopenia, elevated serum angiotensin-converting enzyme levels, hypercalciuria, and thoracic imaging abnormalities consistent with systemic involvement. Treatment with oral methylprednisolone and methotrexate resulted in complete clinical resolution of the cutaneous lesions within three months. This case emphasizes the value of clinicodermoscopic and histopathological correlation in recognizing this rare presentation and prompting evaluation for systemic disease.

Authors

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-10-01
DOI
https://doi.org/10.5281/zenodo.23014653
Primary Topic
Sarcoidosis and Beryllium Toxicity Research
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
article

MICROPAPULAR CUTANEOUS SARCOIDOSIS: CLINICODERMOSCOPIC AND HISTOPATHOLOGICAL CORRELATION

Mustafa Alperen AYDENİZ
Zenodo (CERN European Organization for Nuclear Research)
Sarcoidosis and Beryllium Toxicity Research
article

MICROPAPULAR CUTANEOUS SARCOIDOSIS: CLINICODERMOSCOPIC AND HISTOPATHOLOGICAL CORRELATION

Mustafa Alperen AYDENİZ
article en

Abstract

Sarcoidosis is a multisystem inflammatory disease characterized by noncaseating granulomas, with cutaneous involvement presenting in various morphological patterns. Micropapular cutaneous sarcoidosis is a rare clinical variant that may pose a diagnostic challenge. We report a 64-year-old woman presenting with numerous yellowish-pink millimetric papules on the posterior trunk. Dermoscopy revealed multiple yellow-orange structureless areas on a pink background, while histopathological examination demonstrated non-necrotizing “naked” granulomas with multinucleated giant cells. Systemic evaluation revealed lymphopenia, elevated serum angiotensin-converting enzyme levels, hypercalciuria, and thoracic imaging abnormalities consistent with systemic involvement. Treatment with oral methylprednisolone and methotrexate resulted in complete clinical resolution of the cutaneous lesions within three months. This case emphasizes the value of clinicodermoscopic and histopathological correlation in recognizing this rare presentation and prompting evaluation for systemic disease.

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 13%
Sarcoidosis and Beryllium Toxicity Research
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

MICROPAPULAR CUTANEOUS SARCOIDOSIS: CLINICODERMOSCOPIC AND HISTOPATHOLOGICAL CORRELATION — Mustafa Alperen AYDENİZ · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS