THEORY OF OBJECTS. ARTICLE 16 . 14 META-COMPARTMENT: MUCOUS SECRETIONS OF THE RESPIRATORY TRACT. MUCOUS SECRETIONS OF THE RESPIRATORY TRACT AS A PROTECTIVE BARRIER OF THE LUNGS: PP/IT PROFILE AND RESTORATION OF METABOLIC DIVERSITY IN PEOPLE 55+

The mucous secretions of the respiratory tract are a complex biological environment containing defensins, secretory IgA, mucins, antimicrobial peptides, cytokines, and microbiota products that provide protection for the respiratory system. After the age of 55, the metabolomic diversity of mucous secretions decreases sharply: the number of detected metabolites drops from more than 1700 to a critical threshold of less than 100, which is associated with pneumonia, SARS, COPD, bronchial asthma, cystic fibrosis, bronchiectasis, and accelerated lung aging. However, standard clinical tests do not assess the metabolomic diversity of mucous secretions. The article shows how the theory of objects allows you to measure the metabolic depletion of the mucous secretions of the respiratory tract, what diseases are associated with it, and how foods with a high PC/IT profile, including biogenic nutrition, restore metabolomic diversity. The PP/IT profile is a format for representing two independent indices: the density of objects (PP) and the toxicity index (IT). The entry 250/8 means 250 beneficial molecular species and 8 harmful ones per 100 g of product — this is not a fraction, but two independent numbers side by side, like a blood pressure of 120/80. The profile is tied to the vector of product parameters: variety, origin, method of production, condition, freshness, and storage conditions. A monitoring protocol and practical recommendations for people 55+ are proposed.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-09-28
DOI
https://doi.org/10.5281/zenodo.23014397
Primary Topic
Gut microbiota and health
Type
preprint
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THEORY OF OBJECTS. ARTICLE 16 . 14 META-COMPARTMENT: MUCOUS SECRETIONS OF THE RESPIRATORY TRACT. MUCOUS SECRETIONS OF THE RESPIRATORY TRACT AS A PROTECTIVE BARRIER OF THE LUNGS: PP/IT PROFILE AND RESTORATION OF METABOLIC DIVERSITY IN PEOPLE 55+

Лагода
Zenodo (CERN European Organization for Nuclear Research)
Gut microbiota and health
preprint

THEORY OF OBJECTS. ARTICLE 16 . 14 META-COMPARTMENT: MUCOUS SECRETIONS OF THE RESPIRATORY TRACT. MUCOUS SECRETIONS OF THE RESPIRATORY TRACT AS A PROTECTIVE BARRIER OF THE LUNGS: PP/IT PROFILE AND RESTORATION OF METABOLIC DIVERSITY IN PEOPLE 55+

Лагода
preprint en

Abstract

The mucous secretions of the respiratory tract are a complex biological environment containing defensins, secretory IgA, mucins, antimicrobial peptides, cytokines, and microbiota products that provide protection for the respiratory system. After the age of 55, the metabolomic diversity of mucous secretions decreases sharply: the number of detected metabolites drops from more than 1700 to a critical threshold of less than 100, which is associated with pneumonia, SARS, COPD, bronchial asthma, cystic fibrosis, bronchiectasis, and accelerated lung aging. However, standard clinical tests do not assess the metabolomic diversity of mucous secretions. The article shows how the theory of objects allows you to measure the metabolic depletion of the mucous secretions of the respiratory tract, what diseases are associated with it, and how foods with a high PC/IT profile, including biogenic nutrition, restore metabolomic diversity. The PP/IT profile is a format for representing two independent indices: the density of objects (PP) and the toxicity index (IT). The entry 250/8 means 250 beneficial molecular species and 8 harmful ones per 100 g of product — this is not a fraction, but two independent numbers side by side, like a blood pressure of 120/80. The profile is tied to the vector of product parameters: variety, origin, method of production, condition, freshness, and storage conditions. A monitoring protocol and practical recommendations for people 55+ are proposed.

Zenodo (CERN European Organization for Nuclear Research)
Life in Land
Gut microbiota and health
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THEORY OF OBJECTS. ARTICLE 16 . 14 META-COMPARTMENT: MUCOUS SECRETIONS OF THE RESPIRATORY TRACT. MUCOUS SECRETIONS OF THE RESPIRATORY TRACT AS A PROTECTIVE BARRIER OF THE LUNGS: PP/IT PROFILE AND RESTORATION OF METABOLIC DIVERSITY IN PEOPLE 55+ — Лагода · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS