Safety of Pulsed Field Ablation: Established Evidence, Emerging Risks, and Knowledge Gaps

Pulsed field ablation (PFA) has rapidly emerged as an important ablation technology for atrial arrhythmias and is increasingly being explored for ventricular arrhythmias. As clinical experience expands, a precise understanding of its safety profile is essential. This review summarizes contemporary evidence on the safety of PFA, distinguishes procedure-related complications from those attributable to electroporation, and highlights areas in which evidence remains limited.

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Publication Details

Journal
Pacing and Clinical Electrophysiology
Published
2026-09-25
DOI
https://doi.org/10.1111/pace.70446
Primary Topic
Cardiac Arrhythmias and Treatments
Type
article
Field-Weighted Citation Impact
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article

Safety of Pulsed Field Ablation: Established Evidence, Emerging Risks, and Knowledge Gaps

Boldizsar Kovacs, Jackson Jeikai Liang, Dakota De Cecco, Jeanne du Fay de Lavallaz
Pacing and Clinical Electrophysiology
Cardiac Arrhythmias and Treatments
article

Safety of Pulsed Field Ablation: Established Evidence, Emerging Risks, and Knowledge Gaps

Boldizsar Kovacs, Jackson Jeikai Liang, Dakota De Cecco, Jeanne du Fay de Lavallaz
article en

Abstract

Pulsed field ablation (PFA) has rapidly emerged as an important ablation technology for atrial arrhythmias and is increasingly being explored for ventricular arrhythmias. As clinical experience expands, a precise understanding of its safety profile is essential. This review summarizes contemporary evidence on the safety of PFA, distinguishes procedure-related complications from those attributable to electroporation, and highlights areas in which evidence remains limited.

Pacing and Clinical Electrophysiology
University of Bern (CH), University of Michigan (US), University Hospital of Bern (CH), Michigan Medicine (US)
Openalex Percentile: Top 11%
Cardiac Arrhythmias and Treatments
DOIOpen Access PDFOpenAlex
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Safety of Pulsed Field Ablation: Established Evidence, Emerging Risks, and Knowledge Gaps — Boldizsar Kovacs, Jackson Jeikai Liang, et al. · Pacing and Clinical Electrophysiology (2026) | TGRS Research Map | TGRS