Current concepts in isolated and combined injuries of the medial collateral ligament complex, part II: The anteromedial knee instability classification

Abstract The medial collateral ligament (MCL) has a strong self‐healing capacity; nevertheless, not every MCL injury heals adequately. Persisting medial and anteromedial knee laxity should be avoided as it may lead to increased strains and wear of the surrounding tissue, including the anterior cruciate ligament (ACL), meniscus and cartilage. Better understanding of MCL anatomy and biomechanics, especially in combined ACL‐MCL injuries, has necessitated the need for updated clinical examination, classification and treatment approaches. The newly introduced anteromedial knee instability (AMKI) classification is a clinically and biomechanically based classification system designed to grade medial and anteromedial knee laxity using a structured three‐letter‐based system. First, an injury to the posteromedial complex and the posterior oblique ligament needs to be ruled out by testing valgus laxity in full individual knee extension. The inability to fully extend the knee might lead to a false positive result. Medial laxity is then assessed at 20°–30° of knee flexion. A Grade A injury is defined by a normal clinical valgus stress test indicating an intact superficial MCL (sMCL), but a positive external rotation test, suggesting an isolated injury to the deep MCL (dMCL). Grade B is characterised by a nearly normal or abnormal valgus laxity, combined with a nearly normal or abnormal external rotation test, indicating mild to moderate injuries to both the dMCL and sMCL with or without additional ACL injury. A Grade C injury represents a high‐grade injury pattern, with both severely abnormal valgus laxity and external rotation testing, suggesting a complete injury to the medial stabilisers, often but not necessarily in combination with ACL insufficiency. Treatment of isolated MCL or combined ACL‐MCL injuries is complex and multifactorial, but can be individualised based on the AMKI classification. Level of Evidence Level V.

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Journal
Knee Surgery Sports Traumatology Arthroscopy
Published
2026-09-25
DOI
https://doi.org/10.1002/ksa.70630
Primary Topic
Knee injuries and reconstruction techniques
Type
article
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article

Current concepts in isolated and combined injuries of the medial collateral ligament complex, part II: The anteromedial knee instability classification

Christian Hoser, Nicolas Bouguennec, Gilbert Moatshe, Riccardo Cristiani et al.
Knee Surgery Sports Traumatology Arthroscopy
Knee injuries and reconstruction techniques
article

Current concepts in isolated and combined injuries of the medial collateral ligament complex, part II: The anteromedial knee instability classification

Christian Hoser, Nicolas Bouguennec, Gilbert Moatshe, Riccardo Cristiani, Armin Runer, Volker Musahl, Lukas Willinger, Riccardo D’Ambrosi, Mirco Herbort, Alan M. J. Getgood, Elisabeth Abermann, Guido Wierer, Andy M. Williams, Marc Jacob Strauss, Christoph Kittl, Robert Śmigielski, James Robinson, Elmar Herbst, Eric Hamrin Senorski, Simon Ball, Martin Lind, Christian Fink, Andrew Amis, Sebastian Siebenlist, Kristian Samuelsson
article en

Abstract

Abstract The medial collateral ligament (MCL) has a strong self‐healing capacity; nevertheless, not every MCL injury heals adequately. Persisting medial and anteromedial knee laxity should be avoided as it may lead to increased strains and wear of the surrounding tissue, including the anterior cruciate ligament (ACL), meniscus and cartilage. Better understanding of MCL anatomy and biomechanics, especially in combined ACL‐MCL injuries, has necessitated the need for updated clinical examination, classification and treatment approaches. The newly introduced anteromedial knee instability (AMKI) classification is a clinically and biomechanically based classification system designed to grade medial and anteromedial knee laxity using a structured three‐letter‐based system. First, an injury to the posteromedial complex and the posterior oblique ligament needs to be ruled out by testing valgus laxity in full individual knee extension. The inability to fully extend the knee might lead to a false positive result. Medial laxity is then assessed at 20°–30° of knee flexion. A Grade A injury is defined by a normal clinical valgus stress test indicating an intact superficial MCL (sMCL), but a positive external rotation test, suggesting an isolated injury to the deep MCL (dMCL). Grade B is characterised by a nearly normal or abnormal valgus laxity, combined with a nearly normal or abnormal external rotation test, indicating mild to moderate injuries to both the dMCL and sMCL with or without additional ACL injury. A Grade C injury represents a high‐grade injury pattern, with both severely abnormal valgus laxity and external rotation testing, suggesting a complete injury to the medial stabilisers, often but not necessarily in combination with ACL insufficiency. Treatment of isolated MCL or combined ACL‐MCL injuries is complex and multifactorial, but can be individualised based on the AMKI classification. Level of Evidence Level V.

Knee Surgery Sports Traumatology Arthroscopy
University of Oslo (NO), University of Milan (IT), Medical University of Warsaw (PL), Freddie Mac (United States) (US), Paracelsus Medical University (AT), At Bristol (GB), Aarhus University Hospital (DK), TUM Klinikum (DE), Karolinska Institutet (SE), Qatar Orthopaedic and Sports Medicine Hospital (QA), Augenstern (DE), Clinique du Sport (FR), IRCCS Ospedale Galeazzi - Sant'Ambrogio (IT), UMIT - Private Universität für Gesundheitswissenschaften, Medizinische Informatik und Technik (AT), München Klinik (DE), Fortius Clinic (GB), Gelenkpunkt (AT), Imperial College London (GB), University of Gothenburg (SE)
Good health and well-being
Openalex Percentile: Top 9%
Knee injuries and reconstruction techniques
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