AO Spine Clinical Practice Recommendations for Mild Degenerative Cervical Myelopathy: Contemporary Concepts

Study Design Literature review with critical appraisal and clinical recommendations. Objective To highlight contemporary concepts involving the management of mild degenerative cervical myelopathy (DCM) and facilitate integration into clinical practice. Methods Four articles relating to mild DCM were selected and critically appraised. Clinical practice recommendations were developed and evaluated using the GRADE framework and expert opinion. Results Based on low evidence in the Tetreault et al paper, it is conditionally recommended that the severity of DCM should be based on the mJOA score with the following thresholds: mild (15–17), moderate (12–14), and severe (≤11). No clinical recommendation , based on very low level of evidence for the Al-Shawwa et al article, on the routine use of MRI parameters to predict neurological deterioration or guide decisions on timing of surgical intervention in mild DCM. With low quality evidence presented by Badhiwala et al, there is a conditional recommendation for surgery in mild DCM patients with high levels of baseline pain and Neck Disability Index scores. A conditional recommendation , based on very low quality of evidence in the Ozaki et al paper, is that patients should be counseled that upper extremity sensory deficits frequently persist after decompression and that angular-edged spinal cord deformity on axial MRI should be considered a risk factor for residual postoperative upper extremity sensory impairment. Conclusions The management of mild DCM is an evolving field. Using established nomenclature and understanding the nuances of clinical and radiographic presentation may allow for more appropriate counselling and surgical candidate selection.

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Publication Details

Journal
Global Spine Journal
Published
2026-09-24
DOI
https://doi.org/10.1177/21925682261492222
Primary Topic
Cervical and Thoracic Myelopathy
Type
article
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article

AO Spine Clinical Practice Recommendations for Mild Degenerative Cervical Myelopathy: Contemporary Concepts

Mahmoud Fouad Ibrahim, Michael George Fehlings, Nader Hejrati, Konstantinos D. Margetis et al.
Global Spine Journal
Cervical and Thoracic Myelopathy
article

AO Spine Clinical Practice Recommendations for Mild Degenerative Cervical Myelopathy: Contemporary Concepts

Mahmoud Fouad Ibrahim, Michael George Fehlings, Nader Hejrati, Konstantinos D. Margetis, Charles André Carazzo, Lukas Grassner, Chris J. Neal, Paul M. Arnold, Aminul I. Ahmed, Ricardo Rodrigues-Pinto, David B. Anderson, James Harrop, Nathan Evaniew, Carl Zipser, Shekar Kurpad, Nitin Agarwal, Lindsay Tetreault, Charles G. Fisher
article en

Abstract

Study Design Literature review with critical appraisal and clinical recommendations. Objective To highlight contemporary concepts involving the management of mild degenerative cervical myelopathy (DCM) and facilitate integration into clinical practice. Methods Four articles relating to mild DCM were selected and critically appraised. Clinical practice recommendations were developed and evaluated using the GRADE framework and expert opinion. Results Based on low evidence in the Tetreault et al paper, it is conditionally recommended that the severity of DCM should be based on the mJOA score with the following thresholds: mild (15–17), moderate (12–14), and severe (≤11). No clinical recommendation , based on very low level of evidence for the Al-Shawwa et al article, on the routine use of MRI parameters to predict neurological deterioration or guide decisions on timing of surgical intervention in mild DCM. With low quality evidence presented by Badhiwala et al, there is a conditional recommendation for surgery in mild DCM patients with high levels of baseline pain and Neck Disability Index scores. A conditional recommendation , based on very low quality of evidence in the Ozaki et al paper, is that patients should be counseled that upper extremity sensory deficits frequently persist after decompression and that angular-edged spinal cord deformity on axial MRI should be considered a risk factor for residual postoperative upper extremity sensory impairment. Conclusions The management of mild DCM is an evolving field. Using established nomenclature and understanding the nuances of clinical and radiographic presentation may allow for more appropriate counselling and surgical candidate selection.

Global Spine Journal
The University of Sydney (AU), Loyola University Medical Center (US), Froedtert Hospital (US), Maine Medical Center (US), University of British Columbia (CA), Thomas Jefferson University (US), University of Calgary (CA), University of Pittsburgh (US), Universidade do Porto (PT), King's College London (GB), University of Toronto (CA), University of Zurich (CH), Medical College of Wisconsin (US), Paracelsus Medical University (AT), Hospital São Vicente (BR), Maine Medical Center (US), Assiut University Hospitals (EG), Universitätsklinik Balgrist (CH), Hospital de Santo António (PT), OST - Ostschweizer Fachhochschule (CH), Mass General Brigham (US), Assiut University (EG), Icahn School of Medicine at Mount Sinai (US)
Quality Education
Openalex Percentile: Top 8%
Cervical and Thoracic Myelopathy
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