18F-FET PET Pitfall in Pituitary Imaging: False-positive Uptake Due to Neurosarcoidosis
We report a rare pituitary imaging pitfall on 18F-FET PET/CT in a 38-year-old man with a history of treated pulmonary sarcoidosis. MRIs demonstrated a left-sided pituitary neuroendocrine tumor (PitNET)/pituitary adenoma. 18F-FET PET/CT showed discordant bilateral uptake with higher activity on the right side. Histopathological analysis demonstrated a PitNET of corticotroph type on the left side and noncaseating granulomas consistent with sarcoidosis on the right side. Neurosarcoidosis should be considered a potential cause of false-positive 18F-FET uptake.
Authors
- Anthime Flaus (ORCID: https://orcid.org/0000-0001-5877-2159)
- Alexandre Vasiljevic (ORCID: https://orcid.org/0000-0001-5954-0317)
- Camille Sergeant (ORCID: https://orcid.org/0009-0009-8182-5955)
- Emmanuel Jouanneau (ORCID: https://orcid.org/0000-0003-2506-3430)
- Gérald Raverot
- Chloé Merino
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Hospices Civils de Lyon (FR)
- Centre de Recherche en Cancérologie de Lyon (FR)
Publication Details
- Journal
- Clinical Nuclear Medicine
- Published
- 2026-09-24
- DOI
- https://doi.org/10.1097/rlu.0000000000006651
- Primary Topic
- Sarcoidosis and Beryllium Toxicity Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00