Surgical Management of Lacrimal Gland Tumors

Epithelial lacrimal gland tumors are rare but important to diagnose early. The initial surgical decision to do an incisional biopsy versus gross total resection depends largely on the radiologic characteristics of the lacrimal gland mass. Until recently, orbital exenteration was considered the standard surgical approach for malignant epithelial tumors of the lacrimal gland. However, more recently, eye-sparing surgical resection followed by radiation therapy has gained popularity in selected patients. In this manuscript, we will review the typical clinical and radiologic features of pleomorphic adenoma of the lacrimal gland compared with those of lacrimal gland carcinoma, and we will review published data regarding local control and survival for malignant lacrimal gland tumors with eye-sparing surgery and radiation.

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Journal
International Ophthalmology Clinics
Published
2026-09-24
DOI
https://doi.org/10.1097/iio.0000000000000640
Primary Topic
Salivary Gland Tumors Diagnosis and Treatment
Type
article
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article

Surgical Management of Lacrimal Gland Tumors

Sara Kamali Zonouzi, Bita Esmaeli, J. Matthew Debnam, Maria de la Garza et al.
International Ophthalmology Clinics
Salivary Gland Tumors Diagnosis and Treatment
article

Surgical Management of Lacrimal Gland Tumors

Sara Kamali Zonouzi, Bita Esmaeli, J. Matthew Debnam, Maria de la Garza, Patricia Chavez-Barrios
article en

Abstract

Epithelial lacrimal gland tumors are rare but important to diagnose early. The initial surgical decision to do an incisional biopsy versus gross total resection depends largely on the radiologic characteristics of the lacrimal gland mass. Until recently, orbital exenteration was considered the standard surgical approach for malignant epithelial tumors of the lacrimal gland. However, more recently, eye-sparing surgical resection followed by radiation therapy has gained popularity in selected patients. In this manuscript, we will review the typical clinical and radiologic features of pleomorphic adenoma of the lacrimal gland compared with those of lacrimal gland carcinoma, and we will review published data regarding local control and survival for malignant lacrimal gland tumors with eye-sparing surgery and radiation.

International Ophthalmology ClinicsVol. 66(4)
The University of Texas MD Anderson Cancer Center (US), Methodist Hospital (US), Methodist Hospital (US), University of Houston (US), Tehran University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 9%
Salivary Gland Tumors Diagnosis and Treatment
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Surgical Management of Lacrimal Gland Tumors — Sara Kamali Zonouzi, Bita Esmaeli, et al. · International Ophthalmology Clinics (2026) | TGRS Research Map | TGRS