Neutrophil to lymphocyte ratio at stoma site predicts colorectal cancer prognosis

This research examines the connection between the neutrophil-to-lymphocyte ratio (NLR) observed at the stoma site and the prognostic outcomes in patients with colorectal cancer, in comparison to individuals without cancer. By conducting a retrospective analysis of clinical records from 83 colorectal cancer patients and 28 non-cancer controls, we evaluated the variances in NLR levels at the stoma site across the two cohorts and explored the relationship between NLR and patient prognosis. Findings reveal that colorectal cancer patients exhibit a significantly elevated NLR at the stoma site compared to non-cancer patients ( P < 0.05). Furthermore, a high NLR is notably linked to overall survival in those affected by colorectal cancer ( P < 0.05). This research delivers preliminary insights for the prognostic evaluation of colorectal cancer patients.

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Journal
Scientific Reports
Published
2026-09-24
DOI
https://doi.org/10.1038/s41598-026-72668-8
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
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article
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article

Neutrophil to lymphocyte ratio at stoma site predicts colorectal cancer prognosis

Zengtao Bao, Tong Cheng, Wanneng He, Chenglong Gao
Scientific Reports
Inflammatory Biomarkers in Disease Prognosis
article

Neutrophil to lymphocyte ratio at stoma site predicts colorectal cancer prognosis

Zengtao Bao, Tong Cheng, Wanneng He, Chenglong Gao
article en

Abstract

This research examines the connection between the neutrophil-to-lymphocyte ratio (NLR) observed at the stoma site and the prognostic outcomes in patients with colorectal cancer, in comparison to individuals without cancer. By conducting a retrospective analysis of clinical records from 83 colorectal cancer patients and 28 non-cancer controls, we evaluated the variances in NLR levels at the stoma site across the two cohorts and explored the relationship between NLR and patient prognosis. Findings reveal that colorectal cancer patients exhibit a significantly elevated NLR at the stoma site compared to non-cancer patients ( P < 0.05). Furthermore, a high NLR is notably linked to overall survival in those affected by colorectal cancer ( P < 0.05). This research delivers preliminary insights for the prognostic evaluation of colorectal cancer patients.

Scientific Reports
Xuzhou Medical College (CN), Lianyungang Oriental Hospital (CN), The First People’s Hospital of Lianyungang (CN)
Good health and well-being
Openalex Percentile: Top 15%
Inflammatory Biomarkers in Disease Prognosis
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Neutrophil to lymphocyte ratio at stoma site predicts colorectal cancer prognosis — Zengtao Bao, Tong Cheng, et al. · Scientific Reports (2026) | TGRS Research Map | TGRS